{"key":"op_141_IL","page":{"url":"https://ru.bookimed.com/clinics/country=israel/procedure=peresadka-kostnogo-mozga/","procedure":{"id":141,"slug":"peresadka-kostnogo-mozga","name":"Пересадка костного мозга","name_forms":{"plural":{"status":"missing","reason":"not_collected"},"genitive":{"status":"missing","reason":"not_collected"}},"type":"therapy","grammar_number":{"status":"missing","reason":"not_collected"},"parent_id":"oncology","family_attribute":{"status":"missing","reason":"not_collected"}},"country":{"id":1,"iso":"IL","name":"Израиль"},"currency":"USD","data_date":{"status":"missing","reason":"not_collected"}},"pages":{"clinics_url":"https://ru.bookimed.com/clinics/country=israel/procedure=peresadka-kostnogo-mozga/","cost_url":"https://ru.bookimed.com/clinics/country=israel/procedure=peresadka-kostnogo-mozga/cost/","best_url":{"status":"missing","reason":"template not live"}},"price":{"from":79000,"to":190000,"avg":{"value":164000,"method":"median","source":"offers"},"us":{"from":250000,"to":400000},"uk":{"from":140000,"to":230000},"by_technique":{"status":"missing","reason":"not_collected"},"by_city":[{"city":"Рамат-Ган","from":79000},{"city":"Иерусалим","from":135000},{"city":"Тель-Авив","from":95000}],"per_unit":{"status":"missing","reason":"not_collected"},"factors":{"status":"missing","reason":"not_collected"},"tiers":{"source":"offers","items":[{"tier":"premium","min":79000,"max":169000,"median":164000,"count":5}]},"comparison":[{"country_iso":"UA","from":28000,"to":45000},{"country_iso":"FR","from":120000,"to":220000},{"country_iso":"GB","from":140000,"to":230000},{"country_iso":"US","from":250000,"to":400000},{"country_iso":"TR","from":25000,"to":45000},{"country_iso":"MX","from":80000,"to":100000},{"country_iso":"DE","from":120000,"to":185000},{"country_iso":"CA","from":150000,"to":280000},{"country_iso":"AE","from":55000,"to":85000},{"country_iso":"TH","from":70000,"to":85000},{"country_iso":"PL","from":45000,"to":68000},{"country_iso":"KR","from":90000,"to":130000},{"country_iso":"CZ","from":45000,"to":75000},{"country_iso":"AT","from":62000,"to":95000},{"country_iso":"ES","from":99500,"to":125000},{"country_iso":"IT","from":70000,"to":125000},{"country_iso":"CN","from":266000,"to":{"status":"missing","reason":"not_collected"}},{"country_iso":"AU","from":140000,"to":210000},{"country_iso":"IN","from":30000,"to":40000},{"country_iso":"MY","from":38000,"to":60000},{"country_iso":"VN","from":30000,"to":55000},{"country_iso":"BR","from":60000,"to":110000},{"country_iso":"AZ","from":29000,"to":40000},{"country_iso":"EG","from":15000,"to":35000}],"base_country":"US","base_is_fallback":false},"savings":{"pct":68,"variant":">=15%"},"package":{"included":["24-hr nurse services","3 meals per day by nutritionist","Anti-HBC test","Anti-HCVAb test","Anti-HIV test","Biochemistry blood test","Biopsy","Blood tests","Chest X-ray","Complete blood count (CBC)","Complete blood count with cancer markers and a proteinogram","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Echocardiography","Electrocardiogram (ECG)","Head MRI","Hospitalization","PET/CT","Transfer airport-clinic-airport","Сonsultation with an oncohematologist","Consultation with an immunologist","Computerized Bone Mineralometry (CBM)","Consultation with an oncologist"],"excluded":{"status":"missing","reason":"not_collected"},"extra_charges":{"status":"missing","reason":"not_collected"}},"clinics":{"count":7,"items":[{"id":9,"name":"Sheba Medical Center","city":"Ramat Gan","rating":5,"reviews_count":2,"accreditations":["Best Maternity Hospitals 2021 by Newsweek","World's Best Smart Hospitals 2021 by Newsweek","World's Best Hospitals 2021 by Newsweek","World's Best Hospitals 2020 by Newsweek","Joint Commission International","International Organization for Standardization","World's Best Specialized Hospitals 2022 by Newsweek","World's Best Smart Hospitals 2023 by Newsweek","World's Best Hospitals 2022 by Newsweek","World's Best Hospitals 2026 by Newsweek","World's Best Hospitals 2025 by Newsweek"],"rank":1,"has_procedure":true,"why_ranked":"Offers autologous, allogeneic, and haploidentical transplants, including reduced-intensity conditioning. On-site HLA and molecular lab for precise donor matching. 2,000+ transplants performed. JCI-accredited.","bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":[{"id":"69ea81452e1b084bd50d82b2","price":79000,"nights":30,"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Pediatric Bone Marrow Transplantation (BMT) at Sheba Medical Center Advanced, Life-Saving Care for Children with Complex Blood Disorders and Cancers At Sheba Medical Center, pediatric bone marrow transplantation is more than a procedure, it is a comprehensive, highly specialized journey of care, designed to give children the best possible chance at recovery, long-term health, and a full life ahead. As one of the leading pediatric transplant centers worldwide, Sheba combines cutting-edge science, extensive clinical experience, and a deeply compassionate approach tailored to each child and family. A Dedicated Pediatric Transplant Unit Designed for Safety and Comfort The Pediatric Hemato-Oncology and BMT Unit at Sheba is specifically designed to support children during the most delicate phases of treatment. Private, advanced isolation rooms with HEPA air filtration to minimize infection risk Highly trained multidisciplinary teams available 24/7 A child-friendly environment focused on both medical excellence and emotional well-being Each detail is carefully planned to ensure maximum safety, comfort, and continuous monitoring throughout the transplant process. When is Bone Marrow Transplant Needed? BMT is a potentially curative treatment for a wide range of serious conditions. Malignant Diseases (Cancers) Leukemias (ALL, AML, CML) Hodgkin and Non-Hodgkin lymphomas Solid tumors (e.g., neuroblastoma, sarcomas, brain tumors) Non-Malignant Conditions Blood disorders (thalassemia, sickle cell disease, aplastic anemia, Fanconi anemia) Immune deficiencies (SCID, HLH, Wiskott-Aldrich syndrome) Metabolic diseases (e.g., Hurler syndrome, adrenoleukodystrophy) For many of these conditions, BMT offers the only curative option. Types of Pediatric Transplants at Sheba Autologous Transplant (Using the Child’s Own Cells) Used mainly for solid tumors. Stem cells are collected, preserved, and re-infused after intensive therapy without the need for a donor. Allogeneic Transplant (Using Donor Cells) Used for leukemias, genetic diseases, and immune disorders. Donors may include: Fully matched siblings Haploidentical (half-matched) family donors, such as parents Unrelated donors from international registries Cord Blood Transplant Stem cells collected from umbilical cord blood provide an additional option, especially when no matched donor is available. Advanced Donor Matching & Laboratory Precision Finding the right donor is critical. Sheba’s on-site HLA and molecular laboratories use high-resolution DNA testing to ensure the closest possible match. As a full member of international donor programs, Sheba provides access to global donor registries, significantly increasing the chances of finding a suitable donor for every child. Cutting-Edge Transplant Techniques When a perfect donor match is not available, Sheba applies advanced technologies to improve safety and outcomes: T-cell depletion to reduce complications CD34+ cell selection for precise stem cell transplantation Integration with CAR-T therapy for high-risk or relapsed cancers These innovations allow physicians to safely perform transplants even in complex or previously untreatable cases. The Transplant Journey: What to Expect 1. Preparation & Conditioning Children undergo carefully tailored treatment (chemotherapy ± radiation) to prepare the body for new stem cells. 2. Stem Cell Infusion The transplant itself is a simple intravenous infusion, similar to a blood transfusion. 3. Engraftment & Recovery New cells begin forming a healthy immune system—this critical phase is closely monitored in a protected environment. Expert Monitoring & Post-Transplant Care Inpatient Phase (3–6 weeks) Continuous monitoring of blood counts and immune recovery Preventive treatments against infections Nutritional and supportive care Outpatient Phase (Day 30–100+) Monitoring for graft-versus-host disease (GvHD) Advanced testing to confirm successful engraftment Gradual immune system recovery and rehabilitation Long-Term Follow-Up Sheba’s dedicated survivorship clinic supports children as they grow, focusing on: Development and hormonal health Fertility preservation Long-term quality of life Clinical Outcomes & Success Rates Sheba is recognized internationally for its strong clinical outcomes: Leukemia (ALL/AML): ~70–85% success in early remission stages Non-malignant diseases: Often over 90% cure rates with matched donors Primary immunodeficiencies: ~80–90% survival when treated early For high-risk cases, combining CAR-T therapy with BMT has further improved outcomes, offering new hope where options were previously limited. Experience You Can Trust 45–55 pediatric transplants performed annually Extensive experience in high-risk and complex cases Active participation in global registries such as EBMT and IBMTR Collaboration with leading international centers A Patient-First Approach At Sheba, every child is treated as an individual with a personalized plan, a dedicated medical team, and continuous support for the entire family. From diagnosis through recovery, the focus remains on: Safety and clinical excellence Emotional support for children and parents Access to the most advanced therapies available worldwide Hope Through Innovation By combining advanced transplantation techniques, world-class expertise, and compassionate care, Sheba Medical Center stands at the forefront of pediatric bone marrow transplantation helping children overcome life-threatening diseases and move forward to healthy, fulfilling lives."},{"id":"69ea8bad351b7b62560851e3","price":167000,"nights":30,"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Pediatric Allogeneic Bone Marrow Transplant for Leukemia (ALL, AML, CML) Sheba Medical Center – Personalized, Advanced Care for Children JCI-Accredited | Ranked Among the World’s Top 10 Hospitals by Newsweek 2026 At Sheba Medical Center, we understand that a diagnosis of leukemia in a child changes everything for a family. Our Pediatric Bone Marrow Transplant (BMT) program is designed to provide not only world-class medical care, but also reassurance, compassion, and hope at every step. As one of the world’s leading pediatric transplant centers, Sheba combines decades of experience with cutting-edge therapies to perform allogeneic bone marrow transplantation, a transplant using healthy stem cells from a donor, for children with acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML). For children with high-risk, relapsed, or treatment-resistant leukemia, allogeneic transplantation often offers the strongest chance for long-term cure. When is an Allogeneic Bone Marrow Transplant Needed? For many children, leukemia can be successfully treated with chemotherapy. However, in certain situations - such as relapse, resistance to treatment, or aggressive disease, an allogeneic bone marrow transplant becomes the most effective treatment option. In an allogeneic transplant, the child receives healthy stem cells from a donor. These cells rebuild the bone marrow and create a new immune system capable of recognizing and fighting leukemia cells. This approach is commonly recommended for: High-risk ALL or AML Relapsed leukemia Leukemia that does not respond fully to standard therapy Selected cases of CML and other complex hematologic conditions A Personalized Approach to Every Child No two children are the same, and neither are their treatments. At Sheba, every child is evaluated by a multidisciplinary team of pediatric hemato-oncology and transplant specialists who carefully determine the optimal treatment strategy, timing, conditioning regimen, and donor source. Whenever possible, a matched sibling donor is preferred. If a sibling match is not available, Sheba actively secures the best possible alternative donor using advanced matching technologies and international donor registries. Donor options include: Matched unrelated donors through global donor programs Haploidentical (partial-match) family donors, often parents Cord blood transplantation With advanced HLA and molecular laboratories on-site, Sheba performs highly precise donor matching to maximize safety and transplant success. Advanced Transplant Techniques Sheba Medical Center is recognized internationally for utilizing some of the most advanced transplant technologies available today, including: T-cell depletion and CD34+ selection to reduce complications and improve transplant outcomes Integration of CAR-T cell therapy prior to transplant in selected high-risk leukemia cases Access to innovative clinical trials and advanced cellular therapies Personalized conditioning and supportive care protocols tailored for children These advanced approaches allow Sheba to safely treat even highly complex or previously difficult-to-treat cases. World-Class Outcomes Sheba’s Pediatric BMT program consistently achieves outcomes aligned with leading international transplant centers: ALL & AML (first or second remission): approximately 75–85% success rates Improved outcomes in relapsed leukemia through integration of advanced cellular therapies Strong long-term survival and quality of life for pediatric patients Our continuous research, innovation, and clinical expertise help provide children with the best possible opportunity for cure and recovery. Precision, Safety, and Specialized Pediatric Care Children undergoing transplantation are cared for in dedicated pediatric transplant units designed specifically for safety, comfort, and healing. Care includes: Highly protected, child-friendly environments Advanced infection prevention systems Continuous monitoring by experienced pediatric transplant specialists Comprehensive supportive care throughout every phase of treatment and recovery Every aspect of care is adapted to support children physically, emotionally, and developmentally. Care Beyond Treatment A bone marrow transplant is more than a medical procedure - it is a journey for the entire family. At Sheba, families receive continuous guidance, emotional support, and clear communication throughout every stage of care. Our multidisciplinary team includes physicians, nurses, psychologists, social workers, rehabilitation specialists, and international patient coordinators. From diagnosis through long-term follow-up, we remain closely involved, helping each child not only overcome leukemia, but return to a healthy and fulfilling life. Why Families Choose Sheba Leading pediatric transplant center with global recognition Expertise in complex and high-risk leukemia cases Advanced allogeneic transplantation capabilities Ability to secure suitable donors—even without a family match Integration of CAR-T and advanced cellular therapies Multidisciplinary, patient-centered pediatric care Dedicated international patient services for a smooth experience A Message of Hope At Sheba Medical Center, we believe every child deserves access to the most advanced treatments available, delivered with compassion, precision, and unwavering commitment. For children facing leukemia, allogeneic bone marrow transplantation at Sheba is more than a treatment option - it is a pathway toward healing, recovery, and a brighter future."},{"id":"69ea9c222e1b084bd50d82b3","price":79200,"nights":30,"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation)for Pediatric Hodgkin Lymphoma (HL) Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand that a diagnosis of Hodgkin Lymphoma (HL) in a child or adolescent is a deeply emotional experience for the entire family. While many children with Hodgkin Lymphoma respond successfully to standard treatments such as chemotherapy and radiotherapy, some cases require more advanced therapy. For children with relapsed, refractory, or high-risk disease, Autologous Stem Cell Transplantation (ASCT) is a highly effective and well-established treatment approach that can help achieve long-term remission. Our pediatric transplant program combines global expertise, advanced medical technology, and compassionate, family-centered care to support children and families throughout every stage of treatment and recovery. The Role of Autologous Stem Cell Transplantation in Pediatric Hodgkin Lymphoma Autologous Stem Cell Transplantation uses the child’s own healthy stem cells to restore bone marrow function after intensive chemotherapy. This approach plays a central role in treating: Relapsed Hodgkin Lymphoma When Hodgkin Lymphoma returns after initial treatment, ASCT may help achieve deeper disease control and improve long-term outcomes. Refractory Disease For children whose lymphoma does not respond adequately to standard therapy, high-dose chemotherapy followed by stem cell rescue offers a more intensive and effective treatment strategy. High-Risk Disease In selected high-risk cases, ASCT may be recommended as consolidation therapy to strengthen treatment response and reduce the risk of recurrence. How the Treatment Works Stem Cell Collection Before high-dose chemotherapy begins, healthy stem cells are collected from the child’s bloodstream and safely preserved. High-Dose Chemotherapy Children then receive intensive chemotherapy designed to eliminate remaining lymphoma cells throughout the body. Stem Cell Rescue After chemotherapy, the child’s own stem cells are reinfused to restore bone marrow function and support immune system recovery. This process allows doctors to deliver highly effective treatment while helping the body rebuild healthy blood-forming cells. Donor Options – Always a Solution Available Although most children with Hodgkin Lymphoma undergo autologous transplantation using their own stem cells, some complex cases may require an allogeneic (donor) transplant. If a donor-based approach is needed, Sheba Medical Center provides access to multiple donor options: Matched family donors, when available Matched unrelated donors through international registries Haploidentical (half-matched) family donors Cord blood transplantation Using advanced matching technologies and global donor access, our team works to ensure that every child can receive the most suitable transplant option, even when a family match is not available. Advanced Pediatric Transplant Care Children undergoing transplantation at Sheba are treated in dedicated pediatric transplant units designed specifically for young patients and their families. Care includes: Highly protected, child-friendly environments Advanced infection prevention systems Pediatric-specific chemotherapy and transplant protocols Continuous monitoring by experienced pediatric oncology and transplant teams Every aspect of care is adapted to the physical and emotional needs of children. Precision, Safety, and Support Sheba Medical Center utilizes advanced laboratory technology and highly specialized transplant protocols to optimize safety and treatment effectiveness. Our multidisciplinary teams provide comprehensive supportive care throughout every stage of transplantation and recovery. Clinical Expertise in Pediatric Hodgkin Lymphoma Sheba Medical Center is a leading center for pediatric hematologic malignancies, offering: Extensive experience in relapsed and refractory Hodgkin Lymphoma Expertise in Autologous Stem Cell Transplantation High success rates with advanced transplant protocols Long-term follow-up focused on growth, development, and quality of life Our treatment strategies are continuously refined according to the latest international research and clinical advances. Care That Supports the Whole Family We recognize that treating a child means supporting the entire family. At Sheba, families are cared for by a multidisciplinary pediatric team including oncologists, transplant specialists, nurses, psychologists, social workers, and care coordinators. From diagnosis through recovery, families receive clear communication, emotional support, and continuous guidance every step of the way. Why Families Choose Sheba for Pediatric ASCT Leading center for pediatric transplantation in lymphoma Strong expertise in relapsed and refractory Hodgkin Lymphoma Advanced autologous transplant protocols Ability to secure suitable donors when needed Safe, supportive, child-centered care environment Dedicated international patient coordination services A Message of Hope At Sheba Medical Center, we combine advanced medical science with compassionate pediatric care. Through innovative approaches like Autologous Stem Cell Transplantation, we strive to provide children with Hodgkin Lymphoma the strongest possible chance for recovery, while supporting families with confidence, care, and hope throughout the entire journey."},{"id":"69f2f3b36d9272b1c40a64a9","price":169000,"nights":30,"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an oncologist","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Bone Marrow Transplant for Pediatric Osteosarcoma Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand how difficult it is for families to face a diagnosis of osteosarcoma. As the most common primary bone cancer in children and adolescents, it requires highly specialized, coordinated care and strong support for both the child and their loved ones. While most children are successfully treated with a combination of chemotherapy and surgery, bone marrow transplantation (BMT) may be considered in selected, more complex cases, offering an advanced treatment approach when additional therapeutic intensity is needed. Our pediatric transplant program combines leading medical expertise, innovative therapies, and compassionate, family-centered care to support children at every stage of treatment. When is a Bone Marrow Transplant Needed? Bone marrow transplantation is not routinely used for all children with osteosarcoma, but may be recommended in specific situations, including: High-risk disease, particularly when cancer has spread (metastatic osteosarcoma) Relapsed disease, when osteosarcoma returns after initial treatment Cases where a more intensive treatment strategy is appropriate In these settings, BMT allows doctors to deliver high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore bone marrow and support recovery. Types of Transplant Autologous Transplant (Child’s Own Cells) This is the most commonly used transplant approach when BMT is part of osteosarcoma treatment. Stem cells are collected from the child before intensive therapy High-dose chemotherapy is administered The child’s own stem cells are reinfused to rebuild healthy bone marrow This approach enables delivery of higher-dose treatment while supporting safe recovery. Allogeneic Transplant (Donor Cells) In carefully selected cases, Sheba Medical Center also offers allogeneic (donor) transplantation as part of a comprehensive care strategy. This option may be considered when: An alternative stem cell source is needed An immune-based treatment approach may provide additional benefit Donor options at Sheba include: Matched sibling donors Matched unrelated donors from international registries Haploidentical (half-matched) family donors A potential advantage of donor transplantation is the graft-versus-tumor effect, where the new immune system may help identify and target remaining cancer cells. Precision Matching and Advanced Technology Sheba Medical Center utilizes an advanced on-site HLA laboratory for high-resolution genetic testing, ensuring the most accurate donor matching when needed. This precision enhances safety and supports optimal transplant outcomes. Advanced Pediatric Osteosarcoma Care Care at Sheba is highly coordinated and tailored to each child: Integration of chemotherapy, surgery, and transplant strategies Access to innovative and emerging therapies Close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists Comprehensive supportive care throughout treatment Specialized Pediatric Transplant Environment Children receiving BMT are treated in dedicated pediatric transplant units designed for safety and comfort: Child-friendly, highly protected environments Advanced infection prevention systems Continuous care by experienced pediatric specialists Every aspect of care is adapted to support children physically and emotionally. Clinical Expertise Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering: Experience in treating complex and high-risk osteosarcoma cases Expertise in high-dose therapy with stem cell support Outcomes aligned with leading international centers Long-term follow-up focused on growth, recovery, and quality of life Care That Supports the Whole Family We understand that this journey affects the entire family. At Sheba, children and their families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators—ensuring guidance, reassurance, and continuous support throughout treatment. Why Families Choose Sheba for Pediatric BMT Leading pediatric transplant center Expertise in complex bone tumors Access to a wide range of donor options Advanced technologies and treatment approaches Compassionate, child-centered care Dedicated international patient services A Message of Hope At Sheba Medical Center, we combine advanced science with compassionate care to give every child the best possible chance for recovery. Even in complex cases like osteosarcoma, we are committed to supporting families with strength, clarity, and hope every step of the way."},{"id":"69ea8f19dce7cde4a901d1a5","price":164000,"nights":30,"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Pediatric Allogeneic Bone Marrow Transplant for Acute Lymphoblastic Leukemia (ALL) - Using donor cells Sheba Medical Center – Advanced, Personalized Care for Children Roughly two-thirds of pediatric transplants are allogeneic (using cells from a donor), which is the standard curative method for aggressive or relapsed ALL. At Sheba Medical Center, we understand how overwhelming a diagnosis of Acute Lymphoblastic Leukemia (ALL) can be for both children and their families. Our mission is to provide not only the most advanced medical care available, but also reassurance, clarity, and compassionate support throughout every stage of treatment. As a global leader in pediatric hemato-oncology, Sheba offers cutting-edge bone marrow transplantation (BMT) for children with ALL particularly in cases where the disease is high-risk, relapsed, or resistant to standard therapies. When is a Bone Marrow Transplant Needed in ALL? While many children with ALL respond very well to chemotherapy, some require a more intensive approach to achieve a lasting cure. A bone marrow transplant may be recommended when: The leukemia has relapsed The disease is resistant to treatment There are high-risk genetic features A deeper, more durable remission is needed In these situations, BMT replaces the diseased bone marrow with healthy stem cells helping rebuild a new immune system capable of eliminating leukemia cells. A Personalized Treatment Strategy Every child’s condition is unique. At Sheba, treatment decisions are made by a dedicated team of pediatric leukemia and transplant specialists who carefully tailor each plan. Whenever possible, a matched sibling donor is used. If no sibling match is available, we actively secure the most suitable donor using advanced matching technologies and global registries, including: Matched unrelated donors from international donor programs Haploidentical (half-matched) family donors, such as parents Cord blood transplantation Our state-of-the-art HLA and molecular laboratories ensure highly accurate matching, improving safety and transplant success. Advanced Therapies for Better Outcomes Sheba is at the forefront of innovation in pediatric ALL treatment, combining transplantation with the latest breakthroughs: CAR-T cell therapy, often used before transplant in relapsed or refractory ALL to achieve remission T-cell depletion and CD34+ selection reducing complications such as graft-versus-host disease Access to international clinical trials and novel therapies This integrated approach allows us to treat even the most complex cases successfully. Leading Results in Pediatric ALL Sheba’s outcomes for pediatric ALL are among the best internationally: ~70–85% success rates in children undergoing transplant in remission Improved outcomes in relapsed cases through CAR-T integration Strong long-term survival and quality of life Our continuous research and clinical expertise ensure that every child benefits from the most advanced care available today. Care That Supports the Whole Family At Sheba, we treat more than the disease - we care for the child and their family as a whole. Children are treated in specialized, highly protected environments with advanced infection control, while families receive ongoing support, guidance, and clear communication. Our team stays closely involved throughout the entire journey, ensuring each child is supported medically and emotionally on the path to recovery. Why Families Choose Sheba for ALL Treatment Global leader in pediatric leukemia and bone marrow transplantation Expertise in high-risk and relapsed ALL Ability to secure optimal donors even without a family match Integration of CAR-T therapy and advanced cellular treatments Multidisciplinary, patient-centered approach Dedicated services for international families A Message of Hope For children facing Acute Lymphoblastic Leukemia, a bone marrow transplant can offer a real chance for cure. At Sheba Medical Center, we combine advanced science with compassionate care helping children overcome leukemia and move forward toward a healthy, hopeful future."}]},{"id":1,"name":"Sourasky Medical Center (Ichilov)","city":"Tel Aviv","rating":4.5,"reviews_count":172,"accreditations":["World's Best Smart Hospitals 2021 by Newsweek","World's Best Hospitals 2021 by Newsweek","World's Best Hospitals 2020 by Newsweek","Patient choice for Check-up","Fastest treatment organization","Joint Commission International","World's Best Specialized Hospitals 2022 by Newsweek","World's Best Smart Hospitals 2023 by Newsweek","World's Best Hospitals 2022 by Newsweek"],"rank":2,"has_procedure":true,"why_ranked":"The clinic has performed over 300 bone marrow transplants, with a dedicated pediatric department certified by EBMT. It offers comprehensive diagnostics and follow-up care post-transplantation.","bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":16,"name":"Hadassah Medical Center","city":"Jerusalem","rating":4.2,"reviews_count":13,"accreditations":["Nobel Peace Prize","World's Best Hospitals 2021 by Newsweek","World's Best Smart Hospitals 2021 by Newsweek","World's Best Smart Hospitals 2023 by Newsweek"],"rank":3,"has_procedure":true,"why_ranked":"Leads in hematology with specialized bone marrow transplantation techniques. Offers both autologous and allogenic transplants from unrelated donors. Features a dedicated team including Prof. Polina Stepenski for pediatric cases.","bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":17,"name":"Rambam Medical Center","city":"Haifa","rating":5,"reviews_count":2,"accreditations":["Joint Commission International","World's Best Hospitals 2021 by Newsweek","World's Best Smart Hospitals 2023 by Newsweek"],"rank":4,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":4,"name":"Schneider Center for Children Medicine","city":"Petah Tikva","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":["Academy of Osseointegration","Accreditation Canada Diamond Status Level"],"rank":5,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":119,"name":"Herzliya Medical Center","city":"Herzliya","rating":4,"reviews_count":1,"accreditations":{"status":"missing","reason":"not_collected"},"rank":6,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}},{"id":235,"name":"Shaare Zedek Medical Center","city":"Jerusalem","rating":{"status":"missing","reason":"not_collected"},"reviews_count":{"status":"missing","reason":"not_collected"},"accreditations":{"status":"missing","reason":"not_collected"},"rank":7,"has_procedure":true,"why_ranked":{"status":"missing","reason":"not_collected"},"bookimed_stats":{"status":"missing","reason":"not_published"},"procedure_description":{"status":"missing","reason":"not_collected"},"offers":{"status":"missing","reason":"no_offers"}}]},"doctors":{"count":26,"languages":{"status":"missing","reason":"not_collected"}},"cities":[{"id":5,"slug":"ramat-gan","name":"Рамат-Ган","clinics_count":1,"price_from":79000,"profile":{"city_type":"City east of Tel Aviv, Israel","access":["Ben Gurion Airport (TLV), 20 km from Tel Aviv"],"sources":["https://en.wikipedia.org/wiki/Ramat_Gan","https://en.wikipedia.org/wiki/Ben_Gurion_Airport"],"checked_at":"2026-11-03","status":"ok"}},{"id":3,"slug":"ierusalim","name":"Иерусалим","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":135000,"profile":{"city_type":"Historic city in the Judaean Mountains","access":["Ben Gurion Airport (TLV), 45 km from Jerusalem"],"sources":["https://en.wikipedia.org/wiki/Jerusalem","https://en.wikipedia.org/wiki/Ben_Gurion_Airport"],"checked_at":"2026-11-03","status":"ok"}},{"id":2,"slug":"tel-aviv","name":"Тель-Авив","clinics_count":{"status":"missing","reason":"not_collected"},"price_from":95000,"profile":{"city_type":"Mediterranean coastal economic and tech hub","access":["Ben Gurion Airport (TLV), 20 km southeast of city"],"sources":["https://en.wikipedia.org/wiki/Tel_Aviv","https://en.wikipedia.org/wiki/Ben_Gurion_Airport"],"checked_at":"2026-11-03","status":"ok"}}],"offers":{"active":5,"active_with_related":13,"hospital_nights_median":30,"days_in_country_median":{"status":"missing","reason":"fewer than 10 offers with hotel days"},"top_offers":[{"id":"69f13bf0b64b0268790ac872","clinic_id":9,"clinic_listed":true,"price":74500,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an oncologist","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Neuroblastoma Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand how challenging it is for families to face a diagnosis of neuroblastoma. This complex childhood cancer requires not only advanced medical expertise, but also compassionate, family-centered care. For children with high-risk or relapsed neuroblastoma, bone marrow transplantation (BMT) plays a vital role in treatment offering a powerful approach aimed at improving long-term outcomes and giving children the best possible chance for recovery. Our pediatric transplant program combines world-leading expertise, innovative therapies, and a supportive environment designed specifically for children and their families. When is a Bone Marrow Transplant Needed? In neuroblastoma, bone marrow transplantation is typically part of an intensive treatment strategy and may be recommended when: The disease is high-risk at diagnosis Neuroblastoma has spread beyond the original tumor site The disease returns after initial treatment BMT allows doctors to use high-dose therapy to eliminate cancer cells, followed by the infusion of healthy stem cells to restore the bone marrow and immune system. Types of Transplant Autologous Transplant (Child’s Own Cells) For most children with neuroblastoma, this is the standard approach. Stem cells are collected from the child in advance High-dose therapy is delivered to target remaining cancer cells The child’s own cells are reinfused to rebuild healthy bone marrow In selected cases, tandem (double) transplants may be recommended to further strengthen treatment outcomes. Allogeneic Transplant (Donor Cells) While autologous transplantation is the most common approach, Sheba Medical Center also offers advanced allogeneic (donor) transplantation for carefully selected cases. This option may be considered for: Children who need an alternative stem cell source Children who require an additional therapeutic strategy after prior treatment Donor Options at Sheba include: Matched sibling donors, when available Matched unrelated donors through international registries Haploidentical (half-matched) family donors, often a parent Sheba’s expertise allows access to the most suitable donor for every child, ensuring that no patient is left without options. A unique advantage of donor transplantation is the graft-versus-tumor effect, where the new immune system can help recognize and fight any remaining neuroblastoma cells. Precision Matching and Advanced Technology Successful transplantation begins with the best possible donor match. Sheba Medical Center operates an advanced on-site HLA laboratory, performing high-resolution genetic testing to ensure optimal compatibility between donor and child, enhancing safety and treatment effectiveness. Advanced Pediatric Neuroblastoma Care Sheba offers highly specialized treatment tailored to each child: Personalized transplant protocols Integration with immunotherapy and targeted treatments Advanced supportive care to promote recovery Close collaboration between pediatric oncology and transplant teams Specialized Pediatric Transplant Environment Children are treated in dedicated pediatric transplant units designed for safety, comfort, and healing: Child-friendly, highly protected environments Advanced infection prevention systems Continuous care by experienced pediatric specialists Every aspect of care is adapted to support children physically and emotionally. Clinical Expertise Sheba Medical Center is a leading center for pediatric cancer care, offering: Extensive experience in high-risk neuroblastoma Expertise in autologous and donor transplantation approaches Strong outcomes aligned with leading international centers Long-term follow-up focused on growth, development, and quality of life Care That Supports the Whole Family We understand that this journey involves the entire family. At Sheba, children and their families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators ensuring guidance, reassurance, and continuous support at every stage. Why Families Choose Sheba for Pediatric BMT Leading pediatric transplant center Expertise in complex neuroblastoma cases Access to a wide range of donor options Advanced technologies and treatment approaches Child-focused, compassionate care Dedicated international patient services A Message of Hope At Sheba Medical Center, we combine innovation, expertise, and compassionate pediatric care to give every child the strongest possible chance for recovery, while supporting families with confidence, clarity, and hope every step of the way.","is_package":true},{"id":"61cc3d097ea03b73ac484325","clinic_id":1,"clinic_listed":true,"price":150000,"nights":0,"transfer":true,"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["Сonsultation with an oncohematologist","Blood tests","Consumable materials","Medications","Follow-up visit","Individual chamber","Transfer to the clinic"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Included: - stem sell collection from the donor - chemotherapy - 3 month follow up after bone marrow transplantation","is_package":true}],"packages":[{"id":"69ea81452e1b084bd50d82b2","clinic_id":9,"clinic_listed":true,"price":79000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Pediatric Bone Marrow Transplantation (BMT) at Sheba Medical Center Advanced, Life-Saving Care for Children with Complex Blood Disorders and Cancers At Sheba Medical Center, pediatric bone marrow transplantation is more than a procedure, it is a comprehensive, highly specialized journey of care, designed to give children the best possible chance at recovery, long-term health, and a full life ahead. As one of the leading pediatric transplant centers worldwide, Sheba combines cutting-edge science, extensive clinical experience, and a deeply compassionate approach tailored to each child and family. A Dedicated Pediatric Transplant Unit Designed for Safety and Comfort The Pediatric Hemato-Oncology and BMT Unit at Sheba is specifically designed to support children during the most delicate phases of treatment. Private, advanced isolation rooms with HEPA air filtration to minimize infection risk Highly trained multidisciplinary teams available 24/7 A child-friendly environment focused on both medical excellence and emotional well-being Each detail is carefully planned to ensure maximum safety, comfort, and continuous monitoring throughout the transplant process. When is Bone Marrow Transplant Needed? BMT is a potentially curative treatment for a wide range of serious conditions. Malignant Diseases (Cancers) Leukemias (ALL, AML, CML) Hodgkin and Non-Hodgkin lymphomas Solid tumors (e.g., neuroblastoma, sarcomas, brain tumors) Non-Malignant Conditions Blood disorders (thalassemia, sickle cell disease, aplastic anemia, Fanconi anemia) Immune deficiencies (SCID, HLH, Wiskott-Aldrich syndrome) Metabolic diseases (e.g., Hurler syndrome, adrenoleukodystrophy) For many of these conditions, BMT offers the only curative option. Types of Pediatric Transplants at Sheba Autologous Transplant (Using the Child’s Own Cells) Used mainly for solid tumors. Stem cells are collected, preserved, and re-infused after intensive therapy without the need for a donor. Allogeneic Transplant (Using Donor Cells) Used for leukemias, genetic diseases, and immune disorders. Donors may include: Fully matched siblings Haploidentical (half-matched) family donors, such as parents Unrelated donors from international registries Cord Blood Transplant Stem cells collected from umbilical cord blood provide an additional option, especially when no matched donor is available. Advanced Donor Matching & Laboratory Precision Finding the right donor is critical. Sheba’s on-site HLA and molecular laboratories use high-resolution DNA testing to ensure the closest possible match. As a full member of international donor programs, Sheba provides access to global donor registries, significantly increasing the chances of finding a suitable donor for every child. Cutting-Edge Transplant Techniques When a perfect donor match is not available, Sheba applies advanced technologies to improve safety and outcomes: T-cell depletion to reduce complications CD34+ cell selection for precise stem cell transplantation Integration with CAR-T therapy for high-risk or relapsed cancers These innovations allow physicians to safely perform transplants even in complex or previously untreatable cases. The Transplant Journey: What to Expect 1. Preparation & Conditioning Children undergo carefully tailored treatment (chemotherapy ± radiation) to prepare the body for new stem cells. 2. Stem Cell Infusion The transplant itself is a simple intravenous infusion, similar to a blood transfusion. 3. Engraftment & Recovery New cells begin forming a healthy immune system—this critical phase is closely monitored in a protected environment. Expert Monitoring & Post-Transplant Care Inpatient Phase (3–6 weeks) Continuous monitoring of blood counts and immune recovery Preventive treatments against infections Nutritional and supportive care Outpatient Phase (Day 30–100+) Monitoring for graft-versus-host disease (GvHD) Advanced testing to confirm successful engraftment Gradual immune system recovery and rehabilitation Long-Term Follow-Up Sheba’s dedicated survivorship clinic supports children as they grow, focusing on: Development and hormonal health Fertility preservation Long-term quality of life Clinical Outcomes & Success Rates Sheba is recognized internationally for its strong clinical outcomes: Leukemia (ALL/AML): ~70–85% success in early remission stages Non-malignant diseases: Often over 90% cure rates with matched donors Primary immunodeficiencies: ~80–90% survival when treated early For high-risk cases, combining CAR-T therapy with BMT has further improved outcomes, offering new hope where options were previously limited. Experience You Can Trust 45–55 pediatric transplants performed annually Extensive experience in high-risk and complex cases Active participation in global registries such as EBMT and IBMTR Collaboration with leading international centers A Patient-First Approach At Sheba, every child is treated as an individual with a personalized plan, a dedicated medical team, and continuous support for the entire family. From diagnosis through recovery, the focus remains on: Safety and clinical excellence Emotional support for children and parents Access to the most advanced therapies available worldwide Hope Through Innovation By combining advanced transplantation techniques, world-class expertise, and compassionate care, Sheba Medical Center stands at the forefront of pediatric bone marrow transplantation helping children overcome life-threatening diseases and move forward to healthy, fulfilling lives.","is_package":true},{"id":"69ea8bad351b7b62560851e3","clinic_id":9,"clinic_listed":true,"price":167000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Pediatric Allogeneic Bone Marrow Transplant for Leukemia (ALL, AML, CML) Sheba Medical Center – Personalized, Advanced Care for Children JCI-Accredited | Ranked Among the World’s Top 10 Hospitals by Newsweek 2026 At Sheba Medical Center, we understand that a diagnosis of leukemia in a child changes everything for a family. Our Pediatric Bone Marrow Transplant (BMT) program is designed to provide not only world-class medical care, but also reassurance, compassion, and hope at every step. As one of the world’s leading pediatric transplant centers, Sheba combines decades of experience with cutting-edge therapies to perform allogeneic bone marrow transplantation, a transplant using healthy stem cells from a donor, for children with acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML). For children with high-risk, relapsed, or treatment-resistant leukemia, allogeneic transplantation often offers the strongest chance for long-term cure. When is an Allogeneic Bone Marrow Transplant Needed? For many children, leukemia can be successfully treated with chemotherapy. However, in certain situations - such as relapse, resistance to treatment, or aggressive disease, an allogeneic bone marrow transplant becomes the most effective treatment option. In an allogeneic transplant, the child receives healthy stem cells from a donor. These cells rebuild the bone marrow and create a new immune system capable of recognizing and fighting leukemia cells. This approach is commonly recommended for: High-risk ALL or AML Relapsed leukemia Leukemia that does not respond fully to standard therapy Selected cases of CML and other complex hematologic conditions A Personalized Approach to Every Child No two children are the same, and neither are their treatments. At Sheba, every child is evaluated by a multidisciplinary team of pediatric hemato-oncology and transplant specialists who carefully determine the optimal treatment strategy, timing, conditioning regimen, and donor source. Whenever possible, a matched sibling donor is preferred. If a sibling match is not available, Sheba actively secures the best possible alternative donor using advanced matching technologies and international donor registries. Donor options include: Matched unrelated donors through global donor programs Haploidentical (partial-match) family donors, often parents Cord blood transplantation With advanced HLA and molecular laboratories on-site, Sheba performs highly precise donor matching to maximize safety and transplant success. Advanced Transplant Techniques Sheba Medical Center is recognized internationally for utilizing some of the most advanced transplant technologies available today, including: T-cell depletion and CD34+ selection to reduce complications and improve transplant outcomes Integration of CAR-T cell therapy prior to transplant in selected high-risk leukemia cases Access to innovative clinical trials and advanced cellular therapies Personalized conditioning and supportive care protocols tailored for children These advanced approaches allow Sheba to safely treat even highly complex or previously difficult-to-treat cases. World-Class Outcomes Sheba’s Pediatric BMT program consistently achieves outcomes aligned with leading international transplant centers: ALL & AML (first or second remission): approximately 75–85% success rates Improved outcomes in relapsed leukemia through integration of advanced cellular therapies Strong long-term survival and quality of life for pediatric patients Our continuous research, innovation, and clinical expertise help provide children with the best possible opportunity for cure and recovery. Precision, Safety, and Specialized Pediatric Care Children undergoing transplantation are cared for in dedicated pediatric transplant units designed specifically for safety, comfort, and healing. Care includes: Highly protected, child-friendly environments Advanced infection prevention systems Continuous monitoring by experienced pediatric transplant specialists Comprehensive supportive care throughout every phase of treatment and recovery Every aspect of care is adapted to support children physically, emotionally, and developmentally. Care Beyond Treatment A bone marrow transplant is more than a medical procedure - it is a journey for the entire family. At Sheba, families receive continuous guidance, emotional support, and clear communication throughout every stage of care. Our multidisciplinary team includes physicians, nurses, psychologists, social workers, rehabilitation specialists, and international patient coordinators. From diagnosis through long-term follow-up, we remain closely involved, helping each child not only overcome leukemia, but return to a healthy and fulfilling life. Why Families Choose Sheba Leading pediatric transplant center with global recognition Expertise in complex and high-risk leukemia cases Advanced allogeneic transplantation capabilities Ability to secure suitable donors—even without a family match Integration of CAR-T and advanced cellular therapies Multidisciplinary, patient-centered pediatric care Dedicated international patient services for a smooth experience A Message of Hope At Sheba Medical Center, we believe every child deserves access to the most advanced treatments available, delivered with compassion, precision, and unwavering commitment. For children facing leukemia, allogeneic bone marrow transplantation at Sheba is more than a treatment option - it is a pathway toward healing, recovery, and a brighter future.","is_package":true},{"id":"69ea9c222e1b084bd50d82b3","clinic_id":9,"clinic_listed":true,"price":79200,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation)for Pediatric Hodgkin Lymphoma (HL) Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand that a diagnosis of Hodgkin Lymphoma (HL) in a child or adolescent is a deeply emotional experience for the entire family. While many children with Hodgkin Lymphoma respond successfully to standard treatments such as chemotherapy and radiotherapy, some cases require more advanced therapy. For children with relapsed, refractory, or high-risk disease, Autologous Stem Cell Transplantation (ASCT) is a highly effective and well-established treatment approach that can help achieve long-term remission. Our pediatric transplant program combines global expertise, advanced medical technology, and compassionate, family-centered care to support children and families throughout every stage of treatment and recovery. The Role of Autologous Stem Cell Transplantation in Pediatric Hodgkin Lymphoma Autologous Stem Cell Transplantation uses the child’s own healthy stem cells to restore bone marrow function after intensive chemotherapy. This approach plays a central role in treating: Relapsed Hodgkin Lymphoma When Hodgkin Lymphoma returns after initial treatment, ASCT may help achieve deeper disease control and improve long-term outcomes. Refractory Disease For children whose lymphoma does not respond adequately to standard therapy, high-dose chemotherapy followed by stem cell rescue offers a more intensive and effective treatment strategy. High-Risk Disease In selected high-risk cases, ASCT may be recommended as consolidation therapy to strengthen treatment response and reduce the risk of recurrence. How the Treatment Works Stem Cell Collection Before high-dose chemotherapy begins, healthy stem cells are collected from the child’s bloodstream and safely preserved. High-Dose Chemotherapy Children then receive intensive chemotherapy designed to eliminate remaining lymphoma cells throughout the body. Stem Cell Rescue After chemotherapy, the child’s own stem cells are reinfused to restore bone marrow function and support immune system recovery. This process allows doctors to deliver highly effective treatment while helping the body rebuild healthy blood-forming cells. Donor Options – Always a Solution Available Although most children with Hodgkin Lymphoma undergo autologous transplantation using their own stem cells, some complex cases may require an allogeneic (donor) transplant. If a donor-based approach is needed, Sheba Medical Center provides access to multiple donor options: Matched family donors, when available Matched unrelated donors through international registries Haploidentical (half-matched) family donors Cord blood transplantation Using advanced matching technologies and global donor access, our team works to ensure that every child can receive the most suitable transplant option, even when a family match is not available. Advanced Pediatric Transplant Care Children undergoing transplantation at Sheba are treated in dedicated pediatric transplant units designed specifically for young patients and their families. Care includes: Highly protected, child-friendly environments Advanced infection prevention systems Pediatric-specific chemotherapy and transplant protocols Continuous monitoring by experienced pediatric oncology and transplant teams Every aspect of care is adapted to the physical and emotional needs of children. Precision, Safety, and Support Sheba Medical Center utilizes advanced laboratory technology and highly specialized transplant protocols to optimize safety and treatment effectiveness. Our multidisciplinary teams provide comprehensive supportive care throughout every stage of transplantation and recovery. Clinical Expertise in Pediatric Hodgkin Lymphoma Sheba Medical Center is a leading center for pediatric hematologic malignancies, offering: Extensive experience in relapsed and refractory Hodgkin Lymphoma Expertise in Autologous Stem Cell Transplantation High success rates with advanced transplant protocols Long-term follow-up focused on growth, development, and quality of life Our treatment strategies are continuously refined according to the latest international research and clinical advances. Care That Supports the Whole Family We recognize that treating a child means supporting the entire family. At Sheba, families are cared for by a multidisciplinary pediatric team including oncologists, transplant specialists, nurses, psychologists, social workers, and care coordinators. From diagnosis through recovery, families receive clear communication, emotional support, and continuous guidance every step of the way. Why Families Choose Sheba for Pediatric ASCT Leading center for pediatric transplantation in lymphoma Strong expertise in relapsed and refractory Hodgkin Lymphoma Advanced autologous transplant protocols Ability to secure suitable donors when needed Safe, supportive, child-centered care environment Dedicated international patient coordination services A Message of Hope At Sheba Medical Center, we combine advanced medical science with compassionate pediatric care. Through innovative approaches like Autologous Stem Cell Transplantation, we strive to provide children with Hodgkin Lymphoma the strongest possible chance for recovery, while supporting families with confidence, care, and hope throughout the entire journey.","is_package":true},{"id":"69f2f3b36d9272b1c40a64a9","clinic_id":9,"clinic_listed":true,"price":169000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an oncologist","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Bone Marrow Transplant for Pediatric Osteosarcoma Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand how difficult it is for families to face a diagnosis of osteosarcoma. As the most common primary bone cancer in children and adolescents, it requires highly specialized, coordinated care and strong support for both the child and their loved ones. While most children are successfully treated with a combination of chemotherapy and surgery, bone marrow transplantation (BMT) may be considered in selected, more complex cases, offering an advanced treatment approach when additional therapeutic intensity is needed. Our pediatric transplant program combines leading medical expertise, innovative therapies, and compassionate, family-centered care to support children at every stage of treatment. When is a Bone Marrow Transplant Needed? Bone marrow transplantation is not routinely used for all children with osteosarcoma, but may be recommended in specific situations, including: High-risk disease, particularly when cancer has spread (metastatic osteosarcoma) Relapsed disease, when osteosarcoma returns after initial treatment Cases where a more intensive treatment strategy is appropriate In these settings, BMT allows doctors to deliver high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore bone marrow and support recovery. Types of Transplant Autologous Transplant (Child’s Own Cells) This is the most commonly used transplant approach when BMT is part of osteosarcoma treatment. Stem cells are collected from the child before intensive therapy High-dose chemotherapy is administered The child’s own stem cells are reinfused to rebuild healthy bone marrow This approach enables delivery of higher-dose treatment while supporting safe recovery. Allogeneic Transplant (Donor Cells) In carefully selected cases, Sheba Medical Center also offers allogeneic (donor) transplantation as part of a comprehensive care strategy. This option may be considered when: An alternative stem cell source is needed An immune-based treatment approach may provide additional benefit Donor options at Sheba include: Matched sibling donors Matched unrelated donors from international registries Haploidentical (half-matched) family donors A potential advantage of donor transplantation is the graft-versus-tumor effect, where the new immune system may help identify and target remaining cancer cells. Precision Matching and Advanced Technology Sheba Medical Center utilizes an advanced on-site HLA laboratory for high-resolution genetic testing, ensuring the most accurate donor matching when needed. This precision enhances safety and supports optimal transplant outcomes. Advanced Pediatric Osteosarcoma Care Care at Sheba is highly coordinated and tailored to each child: Integration of chemotherapy, surgery, and transplant strategies Access to innovative and emerging therapies Close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists Comprehensive supportive care throughout treatment Specialized Pediatric Transplant Environment Children receiving BMT are treated in dedicated pediatric transplant units designed for safety and comfort: Child-friendly, highly protected environments Advanced infection prevention systems Continuous care by experienced pediatric specialists Every aspect of care is adapted to support children physically and emotionally. Clinical Expertise Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering: Experience in treating complex and high-risk osteosarcoma cases Expertise in high-dose therapy with stem cell support Outcomes aligned with leading international centers Long-term follow-up focused on growth, recovery, and quality of life Care That Supports the Whole Family We understand that this journey affects the entire family. At Sheba, children and their families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators—ensuring guidance, reassurance, and continuous support throughout treatment. Why Families Choose Sheba for Pediatric BMT Leading pediatric transplant center Expertise in complex bone tumors Access to a wide range of donor options Advanced technologies and treatment approaches Compassionate, child-centered care Dedicated international patient services A Message of Hope At Sheba Medical Center, we combine advanced science with compassionate care to give every child the best possible chance for recovery. Even in complex cases like osteosarcoma, we are committed to supporting families with strength, clarity, and hope every step of the way.","is_package":true},{"id":"69ea8f19dce7cde4a901d1a5","clinic_id":9,"clinic_listed":true,"price":164000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Pediatric Allogeneic Bone Marrow Transplant for Acute Lymphoblastic Leukemia (ALL) - Using donor cells Sheba Medical Center – Advanced, Personalized Care for Children Roughly two-thirds of pediatric transplants are allogeneic (using cells from a donor), which is the standard curative method for aggressive or relapsed ALL. At Sheba Medical Center, we understand how overwhelming a diagnosis of Acute Lymphoblastic Leukemia (ALL) can be for both children and their families. Our mission is to provide not only the most advanced medical care available, but also reassurance, clarity, and compassionate support throughout every stage of treatment. As a global leader in pediatric hemato-oncology, Sheba offers cutting-edge bone marrow transplantation (BMT) for children with ALL particularly in cases where the disease is high-risk, relapsed, or resistant to standard therapies. When is a Bone Marrow Transplant Needed in ALL? While many children with ALL respond very well to chemotherapy, some require a more intensive approach to achieve a lasting cure. A bone marrow transplant may be recommended when: The leukemia has relapsed The disease is resistant to treatment There are high-risk genetic features A deeper, more durable remission is needed In these situations, BMT replaces the diseased bone marrow with healthy stem cells helping rebuild a new immune system capable of eliminating leukemia cells. A Personalized Treatment Strategy Every child’s condition is unique. At Sheba, treatment decisions are made by a dedicated team of pediatric leukemia and transplant specialists who carefully tailor each plan. Whenever possible, a matched sibling donor is used. If no sibling match is available, we actively secure the most suitable donor using advanced matching technologies and global registries, including: Matched unrelated donors from international donor programs Haploidentical (half-matched) family donors, such as parents Cord blood transplantation Our state-of-the-art HLA and molecular laboratories ensure highly accurate matching, improving safety and transplant success. Advanced Therapies for Better Outcomes Sheba is at the forefront of innovation in pediatric ALL treatment, combining transplantation with the latest breakthroughs: CAR-T cell therapy, often used before transplant in relapsed or refractory ALL to achieve remission T-cell depletion and CD34+ selection reducing complications such as graft-versus-host disease Access to international clinical trials and novel therapies This integrated approach allows us to treat even the most complex cases successfully. Leading Results in Pediatric ALL Sheba’s outcomes for pediatric ALL are among the best internationally: ~70–85% success rates in children undergoing transplant in remission Improved outcomes in relapsed cases through CAR-T integration Strong long-term survival and quality of life Our continuous research and clinical expertise ensure that every child benefits from the most advanced care available today. Care That Supports the Whole Family At Sheba, we treat more than the disease - we care for the child and their family as a whole. Children are treated in specialized, highly protected environments with advanced infection control, while families receive ongoing support, guidance, and clear communication. Our team stays closely involved throughout the entire journey, ensuring each child is supported medically and emotionally on the path to recovery. Why Families Choose Sheba for ALL Treatment Global leader in pediatric leukemia and bone marrow transplantation Expertise in high-risk and relapsed ALL Ability to secure optimal donors even without a family match Integration of CAR-T therapy and advanced cellular treatments Multidisciplinary, patient-centered approach Dedicated services for international families A Message of Hope For children facing Acute Lymphoblastic Leukemia, a bone marrow transplant can offer a real chance for cure. At Sheba Medical Center, we combine advanced science with compassionate care helping children overcome leukemia and move forward toward a healthy, hopeful future.","is_package":true}],"related_packages":[{"id":"69f13bf0b64b0268790ac872","clinic_id":9,"clinic_listed":true,"price":74500,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an oncologist","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Neuroblastoma Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand how challenging it is for families to face a diagnosis of neuroblastoma. This complex childhood cancer requires not only advanced medical expertise, but also compassionate, family-centered care. For children with high-risk or relapsed neuroblastoma, bone marrow transplantation (BMT) plays a vital role in treatment offering a powerful approach aimed at improving long-term outcomes and giving children the best possible chance for recovery. Our pediatric transplant program combines world-leading expertise, innovative therapies, and a supportive environment designed specifically for children and their families. When is a Bone Marrow Transplant Needed? In neuroblastoma, bone marrow transplantation is typically part of an intensive treatment strategy and may be recommended when: The disease is high-risk at diagnosis Neuroblastoma has spread beyond the original tumor site The disease returns after initial treatment BMT allows doctors to use high-dose therapy to eliminate cancer cells, followed by the infusion of healthy stem cells to restore the bone marrow and immune system. Types of Transplant Autologous Transplant (Child’s Own Cells) For most children with neuroblastoma, this is the standard approach. Stem cells are collected from the child in advance High-dose therapy is delivered to target remaining cancer cells The child’s own cells are reinfused to rebuild healthy bone marrow In selected cases, tandem (double) transplants may be recommended to further strengthen treatment outcomes. Allogeneic Transplant (Donor Cells) While autologous transplantation is the most common approach, Sheba Medical Center also offers advanced allogeneic (donor) transplantation for carefully selected cases. This option may be considered for: Children who need an alternative stem cell source Children who require an additional therapeutic strategy after prior treatment Donor Options at Sheba include: Matched sibling donors, when available Matched unrelated donors through international registries Haploidentical (half-matched) family donors, often a parent Sheba’s expertise allows access to the most suitable donor for every child, ensuring that no patient is left without options. A unique advantage of donor transplantation is the graft-versus-tumor effect, where the new immune system can help recognize and fight any remaining neuroblastoma cells. Precision Matching and Advanced Technology Successful transplantation begins with the best possible donor match. Sheba Medical Center operates an advanced on-site HLA laboratory, performing high-resolution genetic testing to ensure optimal compatibility between donor and child, enhancing safety and treatment effectiveness. Advanced Pediatric Neuroblastoma Care Sheba offers highly specialized treatment tailored to each child: Personalized transplant protocols Integration with immunotherapy and targeted treatments Advanced supportive care to promote recovery Close collaboration between pediatric oncology and transplant teams Specialized Pediatric Transplant Environment Children are treated in dedicated pediatric transplant units designed for safety, comfort, and healing: Child-friendly, highly protected environments Advanced infection prevention systems Continuous care by experienced pediatric specialists Every aspect of care is adapted to support children physically and emotionally. Clinical Expertise Sheba Medical Center is a leading center for pediatric cancer care, offering: Extensive experience in high-risk neuroblastoma Expertise in autologous and donor transplantation approaches Strong outcomes aligned with leading international centers Long-term follow-up focused on growth, development, and quality of life Care That Supports the Whole Family We understand that this journey involves the entire family. At Sheba, children and their families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators ensuring guidance, reassurance, and continuous support at every stage. Why Families Choose Sheba for Pediatric BMT Leading pediatric transplant center Expertise in complex neuroblastoma cases Access to a wide range of donor options Advanced technologies and treatment approaches Child-focused, compassionate care Dedicated international patient services A Message of Hope At Sheba Medical Center, we combine innovation, expertise, and compassionate pediatric care to give every child the strongest possible chance for recovery, while supporting families with confidence, clarity, and hope every step of the way.","is_package":true,"operation_id":409,"operation_name":"Complex treatment of neuroblastoma"},{"id":"69ea970a351b7b62560851e4","clinic_id":9,"clinic_listed":true,"price":78900,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation)for Pediatric DLBCL (Diffuse Large B-Cell Lymphoma) at Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand that a diagnosis of DLBCL (Diffuse Large B-Cell Lymphoma) in a child or adolescent is a deeply emotional experience for the entire family. While many children with DLBCL (Diffuse Large B-Cell Lymphoma) respond successfully to standard treatments such as chemotherapy and radiotherapy, some cases require more advanced therapy. For children with relapsed, refractory, or high-risk disease, Autologous Stem Cell Transplantation (ASCT) is a highly effective and well-established treatment approach that can help achieve long-term remission. Our pediatric transplant program combines global expertise, advanced medical technology, and compassionate, family-centered care to support children and families throughout every stage of treatment and recovery. The Role of Autologous Stem Cell Transplantation in Pediatric DLBCL (Diffuse Large B-Cell Lymphoma) Autologous Stem Cell Transplantation uses the child’s own healthy stem cells to restore bone marrow function after intensive chemotherapy. This approach plays a central role in treating: Relapsed DLBCL (Diffuse Large B-Cell Lymphoma) When DLBCL (Diffuse Large B-Cell Lymphoma) returns after initial treatment, ASCT may help achieve deeper disease control and improve long-term outcomes. Refractory Disease For children whose lymphoma does not respond adequately to standard therapy, high-dose chemotherapy followed by stem cell rescue offers a more intensive and effective treatment strategy. High-Risk Disease In selected high-risk cases, ASCT may be recommended as consolidation therapy to strengthen treatment response and reduce the risk of recurrence. How the Treatment Works Stem Cell Collection Before high-dose chemotherapy begins, healthy stem cells are collected from the child’s bloodstream and safely preserved. High-Dose Chemotherapy Children then receive intensive chemotherapy designed to eliminate remaining lymphoma cells throughout the body. Stem Cell Rescue After chemotherapy, the child’s own stem cells are reinfused to restore bone marrow function and support immune system recovery. This process allows doctors to deliver highly effective treatment while helping the body rebuild healthy blood-forming cells. Donor Options – Always a Solution Available Although most children with DLBCL (Diffuse Large B-Cell Lymphoma) undergo autologous transplantation using their own stem cells, some complex cases may require an allogeneic (donor) transplant. If a donor-based approach is needed, Sheba Medical Center provides access to multiple donor options: Matched family donors, when available Matched unrelated donors through international registries Haploidentical (half-matched) family donors Cord blood transplantation Using advanced matching technologies and global donor access, our team works to ensure that every child can receive the most suitable transplant option, even when a family match is not available. Advanced Pediatric Transplant Care Children undergoing transplantation at Sheba are treated in dedicated pediatric transplant units designed specifically for young patients and their families. Care includes: Highly protected, child-friendly environments Advanced infection prevention systems Pediatric-specific chemotherapy and transplant protocols Continuous monitoring by experienced pediatric oncology and transplant teams Every aspect of care is adapted to the physical and emotional needs of children. Precision, Safety, and Support Sheba Medical Center utilizes advanced laboratory technology and highly specialized transplant protocols to optimize safety and treatment effectiveness. Our multidisciplinary teams provide comprehensive supportive care throughout every stage of transplantation and recovery. Clinical Expertise in Pediatric Hodgkin Lymphoma Sheba Medical Center is a leading center for pediatric hematologic malignancies, offering: Extensive experience in relapsed and refractory DLBCL (Diffuse Large B-Cell Lymphoma) Expertise in Autologous Stem Cell Transplantation High success rates with advanced transplant protocols Long-term follow-up focused on growth, development, and quality of life Our treatment strategies are continuously refined according to the latest international research and clinical advances. Care That Supports the Whole Family We recognize that treating a child means supporting the entire family. At Sheba, families are cared for by a multidisciplinary pediatric team including oncologists, transplant specialists, nurses, psychologists, social workers, and care coordinators. From diagnosis through recovery, families receive clear communication, emotional support, and continuous guidance every step of the way. Why Families Choose Sheba for Pediatric ASCT Leading center for pediatric transplantation in lymphoma Strong expertise in relapsed and refractory DLBCL (Diffuse Large B-Cell Lymphoma) Advanced autologous transplant protocols Ability to secure suitable donors when needed Safe, supportive, child-centered care environment Dedicated international patient coordination services A Message of Hope At Sheba Medical Center, we combine advanced medical science with compassionate pediatric care. Through innovative approaches like Autologous Stem Cell Transplantation, we strive to provide children with DLBCL (Diffuse Large B-Cell Lymphoma) the strongest possible chance for recovery, while supporting families with confidence, care, and hope throughout the entire journey.","is_package":true,"operation_id":176,"operation_name":"Autologous bone marrow transplantation"},{"id":"69f13f861ab36766a802e3c2","clinic_id":9,"clinic_listed":true,"price":79000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Ewing Sarcoma Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand how overwhelming it can be for families to face a diagnosis of Ewing Sarcoma. This rare and aggressive childhood cancer requires highly specialized care, precision treatment, and a deeply supportive environment for both the child and their family. For children with high-risk, recurrent, or treatment-resistant Ewing Sarcoma, Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) may be considered as part of an advanced treatment strategy, offering a powerful approach aimed at improving long-term outcomes. Our pediatric transplant program combines world-class expertise, innovative therapies, and compassionate, family-centered care at every stage of the journey. When is a Bone Marrow Transplant Needed? Bone marrow transplantation is not part of standard treatment for all children with Ewing Sarcoma, but is recommended in specific situations, including: High-risk disease, particularly with spread beyond the primary tumor Relapsed Ewing Sarcoma, when the disease returns after initial treatment Refractory disease, when standard therapies are not sufficient In these cases, BMT allows the use of high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore the bone marrow and immune system. Types of Transplant Autologous Transplant (Child’s Own Cells) This is the most commonly used transplant approach in Ewing Sarcoma when BMT is indicated. Stem cells are collected from the child in advance Intensive therapy is administered to eliminate cancer cells The child’s own stem cells are reinfused to support recovery This approach enables the safe delivery of higher-intensity treatment. Advanced Pediatric Sarcoma Care Treatment for Ewing Sarcoma at Sheba is highly coordinated and personalized: Integration of chemotherapy, surgery, and radiotherapy with transplant strategies Access to innovative and targeted therapies when appropriate Close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists Advanced supportive care throughout treatment Specialized Pediatric Transplant Environment Children undergoing transplantation are cared for in dedicated pediatric units designed to support healing and comfort: Child-friendly, protected environments Advanced infection prevention systems Continuous monitoring by experienced pediatric teams Every aspect of care is tailored to the needs of growing children. Clinical Expertise Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering: Experience in managing complex and high-risk Ewing Sarcoma cases Expertise in high-dose therapy with stem cell support Outcomes aligned with leading international centers Long-term follow-up focused on recovery, growth, and quality of life Care That Supports the Whole Family We understand that treating a child means supporting the entire family. At Sheba, families are guided by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators ensuring clear communication, emotional support, and continuity of care throughout the journey. Why Families Choose Sheba for Pediatric BMT Leading pediatric transplant center Expertise in rare and complex sarcomas Access to a wide range of donor options Advanced treatment technologies Compassionate, child-centered care Dedicated international patient services A Message of Hope At Sheba Medical Center, we combine advanced science with compassionate pediatric care. Even in complex conditions like Ewing Sarcoma, our goal is to provide every child with the strongest possible chance for recovery—while supporting families with confidence, care, and hope every step of the way.","is_package":true,"operation_id":479,"operation_name":"Complex treatment of Ewing's sarcoma"},{"id":"69f2f53feb3b0d33c6041a74","clinic_id":9,"clinic_listed":true,"price":78000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an oncologist","Consultation with a hematologist","Consultation with an immunologist","Consultation with a nephrologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) for Pediatric Wilms’ Tumor at Sheba Hospital Sheba Medical Center – Advanced, Personalized Transplant Care for Children At Sheba Medical Center, we understand how overwhelming it can be for families to face a diagnosis of Wilms’ tumor. As one of the most common kidney cancers in children, it is often highly treatable, but in some cases, more advanced care is needed. For children with high-risk, relapsed, or treatment-resistant Wilms’ tumor, Autologous Stem Cell Transplantation (Autologous Bone Marrow Transplantation) is a part of a comprehensive treatment approach offering an additional option aimed at improving long-term outcomes. Our pediatric transplant program combines world-class expertise, innovative therapies, and compassionate, family-centered care to support children and their families throughout every stage of treatment. When is a Bone Marrow Transplant Needed? Bone marrow transplantation is not routinely required for most children with Wilms’ tumor, but may be recommended in specific situations, including: High-risk disease, particularly with spread beyond the kidney Relapsed Wilms’ tumor, when the disease returns after initial treatment Cases where a more intensive treatment strategy is needed In these cases, BMT allows doctors to deliver high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore bone marrow and support recovery. Types of Transplant Autologous Transplant (Child’s Own Cells) This is the most commonly used transplant approach when BMT is part of treatment for Wilms’ tumor. Stem cells are collected from the child before intensive therapy High-dose chemotherapy is administered The child’s own stem cells are reinfused to rebuild healthy bone marrow This approach enables effective treatment while supporting safe recovery. Advanced Pediatric Wilms’ Tumor Care Treatment at Sheba is highly coordinated and tailored to each child: Integration of chemotherapy, surgery, and radiotherapy with transplant strategies Access to innovative and targeted therapies when appropriate Close collaboration between pediatric oncologists, surgeons, and transplant specialists Comprehensive supportive care throughout treatment Specialized Pediatric Transplant Environment Children undergoing BMT are treated in dedicated pediatric transplant units designed for safety, comfort, and healing: Child-friendly, highly protected environments Advanced infection prevention systems Continuous care by experienced pediatric specialists Every aspect of care is adapted to support children physically and emotionally. Clinical Expertise Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering: Experience in managing complex and high-risk Wilms’ tumor cases Expertise in high-dose therapy with stem cell support Outcomes aligned with leading international centers Long-term follow-up focused on recovery, growth, and quality of life Care That Supports the Whole Family We understand that treating a child means caring for the entire family. At Sheba, families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators ensuring guidance, reassurance, and continuous support throughout the journey. Why Families Choose Sheba for Pediatric BMT Leading pediatric transplant center Expertise in complex pediatric cancers Access to a wide range of donor options Advanced treatment technologies Compassionate, child-centered care Dedicated international patient services A Message of Hope At Sheba Medical Center, we combine advanced science with compassionate pediatric care. Even in more complex cases of Wilms’ tumor, our goal is to provide every child with the strongest possible chance for recovery, while supporting families with confidence, care, and hope every step of the way.","is_package":true,"operation_id":561,"operation_name":"Complex treatment of nephroblastoma"},{"id":"69f2f697a4c58f13fe0baf55","clinic_id":9,"clinic_listed":true,"price":79000,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["3 meals per day by nutritionist","24-hr nurse services","Electrocardiogram (ECG)","Blood tests","Chest X-ray","Anti-HIV test","Anti-HBC test","Anti-HCVAb test","Echocardiography","Complete blood count (CBC)","Biochemistry blood test","PET/CT","Consultation with an oncologist","Consultation with a hematologist","Consultation with an immunologist","Consultation with a cardiologist","Consultation with a pediatric hematologist","Consultation with a pediatrician","Сonsultation with an oncohematologist","Head MRI","Biopsy","Computerized Bone Mineralometry (CBM)","Complete blood count with cancer markers and a proteinogram","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Autologous Stem Cell Transplantation for Pediatric Osteosarcoma Sheba Medical Center – Advanced, Personalized Care for Children At Sheba Medical Center, we understand how challenging it can be for families to face a diagnosis of osteosarcoma. As the most common primary bone cancer in children and adolescents, osteosarcoma requires highly specialized treatment and close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists. While many children achieve excellent outcomes with a combination of chemotherapy and surgery, some cases require a more intensive treatment approach. For selected children with advanced, metastatic, or relapsed osteosarcoma, high-dose chemotherapy supported by Autologous Stem Cell Transplantation (ASCT) may offer an additional therapeutic option. At Sheba, we combine world-class expertise, innovative treatment strategies, and compassionate family-centered care to provide every child with the most advanced treatment opportunities available. When is Autologous Stem Cell Transplantation Considered? Autologous Stem Cell Transplantation is not routinely used for all children with osteosarcoma. However, it may be considered in carefully selected situations, including: Metastatic osteosarcoma Relapsed disease High-risk cases requiring intensified treatment Children participating in specialized treatment protocols In these situations, high-dose chemotherapy may be used to target resistant cancer cells. Stem cell transplantation allows doctors to safely administer these intensive treatments while supporting the body's recovery afterward. How the Treatment Works Stem Cell Collection Before treatment begins, healthy blood-forming stem cells are collected from the child's bloodstream and carefully preserved. High-Dose Chemotherapy The child receives intensive chemotherapy designed to target remaining osteosarcoma cells throughout the body. Stem Cell Rescue After chemotherapy, the child's previously collected stem cells are reinfused to restore bone marrow function and support the recovery of healthy blood cells and the immune system. This process allows physicians to deliver highly intensive treatment while helping the body recover efficiently. Advanced Pediatric Sarcoma Care At Sheba Medical Center, every treatment plan is tailored to the individual child. Our multidisciplinary team integrates: Pediatric oncology expertise Advanced orthopedic oncology surgery High-dose chemotherapy protocols Stem cell transplantation when appropriate Innovative supportive care strategies This coordinated approach ensures that every child receives comprehensive care designed around their specific needs. Specialized Pediatric Transplant Environment Children undergoing stem cell transplantation are treated in dedicated pediatric transplant units designed specifically for safety, comfort, and healing. Care includes: Child-friendly treatment environments Advanced infection prevention systems Continuous monitoring by experienced pediatric specialists Comprehensive supportive care throughout treatment and recovery Every aspect of care is focused on helping children and families feel supported throughout their journey. Clinical Expertise Sheba Medical Center is internationally recognized for pediatric cancer care and stem cell transplantation, offering: Extensive experience in treating complex pediatric solid tumors Expertise in high-dose chemotherapy with stem cell support Advanced multidisciplinary sarcoma care Access to innovative treatment approaches and clinical research Long-term follow-up focused on recovery, growth, and quality of life Care That Supports the Whole Family We understand that cancer treatment affects the entire family. At Sheba, families are supported by a multidisciplinary team including physicians, nurses, psychologists, social workers, rehabilitation specialists, and care coordinators. From diagnosis through recovery, we provide guidance, reassurance, and ongoing support every step of the way. Why Families Choose Sheba Leading pediatric oncology and transplant center Expertise in advanced osteosarcoma treatment Experience with high-dose chemotherapy and stem cell support Multidisciplinary care from internationally recognized specialists Child-centered, family-focused approach Dedicated international patient services A Message of Hope At Sheba Medical Center, we believe every child deserves access to the most advanced therapies available. Through innovative treatment strategies, specialized expertise, and compassionate care, we are committed to helping children with osteosarcoma achieve the best possible outcomes while supporting families with confidence, strength, and hope throughout their journey.","is_package":true,"operation_id":{"status":"missing","reason":"not_collected"},"operation_name":{"status":"missing","reason":"not_collected"}},{"id":"69999e916fb9acc3800b73e2","clinic_id":9,"clinic_listed":true,"price":165300,"nights":30,"transfer":{"status":"missing","reason":"not_collected"},"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["24-hr nurse services","CT Scan","Ultrasonography (USG)","Electrocardiogram (ECG)","Local anesthesia","Medications","Ultrasound","СT of one area","Histopathology revision","Consultation with a physician","Сonsultation with an oncohematologist","Biopsy","Full board (breakfast+lunch+dinner+drinks)","Hospitalization","Transfer airport-clinic-airport"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"The treatment is performed by the leading BMT experts at Sheba Medical Center - Israel’s largest and most advanced tertiary hospital, consistently ranked among the Top 10 hospitals worldwide and accredited by JCI. Sheba’s Bone Marrow Transplant Unit operates one of the most efficient donor search coordination systems globally, providing rapid access to international donor registries and cord blood networks - significantly reducing the time to transplantation in urgent and high-risk cases. The comprehensive package includes detailed pre-transplant evaluation, expedited donor identification, individualized conditioning therapy and full inpatient care in a specialized high-isolation transplant unit. Advanced reduced-intensity conditioning protocols, cutting-edge supportive care, and strict infection control standards are applied to optimize outcomes in complex hematologic malignancies.","is_package":true,"operation_id":178,"operation_name":"Allogenic bone marrow transplantation from an unrelated donor"},{"id":"61cc3c5b343c394d3b328dd4","clinic_id":1,"clinic_listed":true,"price":150000,"nights":0,"transfer":true,"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["Consultation with a pediatric hematologist","Consultation with an oncologist","Blood tests","Consumable materials","Medications","Follow-up visit","Individual chamber","Transfer to the clinic"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Included: - stem sell collection from the donor - chemotherapy - 3 month follow up after bone marrow transplantation","is_package":true,"operation_id":178,"operation_name":"Allogenic bone marrow transplantation from an unrelated donor"},{"id":"61cc3d097ea03b73ac484325","clinic_id":1,"clinic_listed":true,"price":150000,"nights":0,"transfer":true,"tests":{"status":"missing","reason":"not_collected"},"meds":{"status":"missing","reason":"not_collected"},"aftercare":{"status":"missing","reason":"not_collected"},"guarantee":{"status":"missing","reason":"not_collected"},"included":["Сonsultation with an oncohematologist","Blood tests","Consumable materials","Medications","Follow-up visit","Individual chamber","Transfer to the clinic"],"excluded":{"status":"missing","reason":"not_collected"},"other_services":"Included: - stem sell collection from the donor - chemotherapy - 3 month follow up after bone marrow transplantation","is_package":true,"operation_id":178,"operation_name":"Allogenic bone marrow transplantation from an unrelated donor"}],"other_packages":{"status":"missing","reason":"not_classified"}},"medical":{"indications":["Hematologic malignancies such as leukemia, lymphoma and multiple myeloma","Myelodysplastic syndromes and myeloproliferative neoplasms","Bone marrow failure such as severe aplastic anemia","Thalassemia major and sickle cell disease in selected patients","Primary immunodeficiencies","Relapsed or high-risk disease needing high-dose chemotherapy rescue"],"contraindications":["Severe uncontrolled active infection","Severe organ dysfunction (heart, lung, liver, kidney) beyond acceptable thresholds","Poor performance status or limited life expectancy from other causes","Active uncontrolled or progressive disease in some settings (relative)","Pregnancy","Lack of suitable donor for allogeneic transplant"],"operation_hours":{"min":0.5,"max":4,"unit":"hours","qualifier":"Infusion itself on transplant day; conditioning and engraftment add days to weeks."},"anesthesia":["local_sedation"],"sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One stem cell infusion within one admission; a second transplant only for graft failure or relapse."},"stages":[{"code":"conditioning","label":"Conditioning chemotherapy with or without radiation","after":{"min":0,"max":0,"unit":"days","qualifier":"Starts about 5-10 days before infusion; counted here as admission start."}},{"code":"stem_cell_infusion","label":"Stem cell infusion","after":{"min":5,"max":10,"unit":"days","qualifier":"Approximate interval after conditioning starts."}}],"qualifier":"One transplant episode: single infusion after conditioning."},"hospital_nights":{"value":30,"source":"offers","parsed_details":{"min":14,"max":35,"unit":"nights","qualifier":"Autologous: about 2–3 weeks. Allogeneic: about 3–5 weeks until engraftment. Complications extend stay."}},"treatment_conditions":["inpatient"],"rehabilitation_days":{"min":60,"max":180,"unit":"days","qualifier":"Daily activities resume in about 1–3 months (autologous) or 3–6 months (allogeneic). Full stamina can take a year."},"fly_home_after_days":{"min":30,"max":100,"unit":"days","qualifier":"Autologous: about 4 weeks after infusion, once counts recover. Allogeneic: usually stay near the center until about day +100."},"back_to_work_days":{"min":90,"max":365,"unit":"days","qualifier":"Autologous: desk work in about 3–6 months. Allogeneic: 6–12 months, longer with GVHD. Often part-time at first."},"exercise_resume_weeks":{"min":13,"max":52,"unit":"weeks","qualifier":"Light activity early. Strenuous exercise after about 3-6 months (autologous) or 6-12 months (allogeneic), if counts and GVHD allow."},"final_result_months":{"min":6,"max":24,"unit":"months","qualifier":"Engraftment takes about 2–4 weeks. Immune recovery and confirmed remission or disease correction take about 6–24 months."},"result_longevity":"Benefit is often lifelong in patients who stay in remission: most relapses occur within 2 years, and disease-free beyond 2–5 years means high cure chance. In non-malignant disorders, engraftment can be permanent.","main_risks":["Serious infections due to prolonged immunosuppression","Graft-versus-host disease (allogeneic)","Graft failure requiring a second transplant","Mucositis, nausea and organ toxicity from conditioning","Bleeding and need for transfusions","Veno-occlusive disease of the liver","Infusion reactions","Infertility and late effects including secondary cancers","Transplant-related mortality"],"complication_rate_pct":{"min":50,"max":80,"unit":"percent","qualifier":"Any significant complication in first year; higher with allogeneic transplant."},"revision_rate_pct":{"min":1,"max":5,"unit":"percent","qualifier":"Second transplant for graft failure, mainly after allogeneic transplant."},"success":{"metric":"Overall survival after transplant","value":50,"horizon":"5 years","source":{"status":"missing","reason":"not_collected"},"evidence_status":"limited"},"scars":"No surgical scar; only a small mark remains at the central venous catheter site.","pain":"The infusion itself is usually painless, similar to a blood transfusion; discomfort mainly comes from conditioning, mouth sores, nausea and other side effects, managed with supportive care.","preparation":["Comprehensive evaluation of disease status, organ function and infection screening","Stem cell collection by apheresis after mobilization (autologous)","Donor HLA matching and donor clearance (allogeneic)","Central venous catheter placement","Conditioning chemotherapy with or without radiation before infusion","Dental and fertility counseling, and arrangement of caregiver support"],"recovery_timeline":[{"phase":"Conditioning and infusion (day -10 to 0)","description":"Conditioning therapy followed by infusion of stem cells over about 30 minutes to a few hours in hospital.","restrictions":["Inpatient protective isolation"]},{"phase":"Aplasia and engraftment (about days 0-30)","description":"Low blood counts until engraftment, with transfusions, 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weeks."}},{"purpose":"assessment","requirement":"routine","after":{"min":90,"max":100,"unit":"days","qualifier":"Day +100 review of GVHD, infections and immunosuppression taper, mainly after allogeneic transplant."}},{"purpose":"result_review","requirement":"routine","after":{"min":180,"max":365,"unit":"days","qualifier":"Disease restaging and chimerism or marrow assessment to confirm remission and immune recovery."}},{"purpose":"other","requirement":"conditional","after":{"min":30,"max":180,"unit":"days","qualifier":"Unscheduled review if fever, infection, GVHD signs or graft problems arise."}}],"sources":{"status":"missing","reason":"not_collected"},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check that you can ask the clinician questions about your treatment during the consultation","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you been able to ask them questions about your treatment?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C2","text":"Check how your aftercare will be coordinated once you return home","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Ensure you're clear about how your aftercare will be coordinated.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C3","text":"Check the qualifications of the medical team treating you","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you checked the qualifications of the medical team treating you?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C4","text":"Check that the clinic provides regular post-transplant check-ups after discharge","scope":"procedure","source":{"url":"https://www.nhs.uk/tests-and-treatments/stem-cell-or-bone-marrow-transplants/recovery/","host":"nhs.uk","quote":"After you leave hospital, you'll have regular check-ups with your care team.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C5","text":"Check that medicines protecting against infection and immune-system complications are provided when needed","scope":"procedure","source":{"url":"https://www.nhs.uk/tests-and-treatments/stem-cell-or-bone-marrow-transplants/recovery/","host":"nhs.uk","quote":"give you medicines to protect from infections; give you medicine to stop your immune system attacking the new stem cells (if they came from a donor)","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C6","text":"Check that the clinic can arrange blood or platelet transfusions when required after transplantation","scope":"procedure","source":{"url":"https://www.nhs.uk/tests-and-treatments/stem-cell-or-bone-marrow-transplants/recovery/","host":"nhs.uk","quote":"arrange for you to have blood or platelet transfusions, if your body has not started to make enough healthy blood cells yet","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"Treatment advice coming from sales staff or agents rather than the treating clinician is a warning sign","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Do not accept advice from a travel agent, sales representatives or administrators.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F2","text":"An advert or information that guarantees complete success should raise concerns","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Any advert or information that guarantees complete success should raise concerns.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F3","text":"Forceful persuasion or cheap, time-limited offers pushing you into a quick decision","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Don’t be pressured into quick decisions either through forceful persuasion or cheap, time limited offers.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Shortness of breath or changes in breathing","urgency":"contact_clinic","general":false,"source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/transplant-side-effects.html","host":"cancer.org","quote":"Report any shortness of breath or changes in your breathing to your transplant team right away.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"W2","text":"Rash or redness on palms and soles","urgency":"contact_clinic","general":false,"source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/transplant-side-effects.html","host":"cancer.org","quote":"A rash, burning, and redness of the skin on the upper chest, palms and soles is often the earliest sign of GVHD.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"W3","text":"Easy bruising and bleeding, such as nosebleeds","urgency":"contact_clinic","general":false,"source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/transplant-side-effects.html","host":"cancer.org","quote":"During this time, you might notice easy bruising and bleeding, such as nosebleeds and bleeding gums.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"W4","text":"Severe diarrhea","urgency":"contact_clinic","general":false,"source":{"url":"https://www.cancerresearchuk.org/about-cancer/treatment/bone-marrow-stem-cell-transplants/side-effects","host":"cancerresearchuk.org","quote":"Tell your team if your diarrhoea is severe.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"W5","text":"Fever","urgency":"contact_clinic","general":true,"source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/transplant-side-effects.html","host":"cancer.org","quote":"It's very important to contact your transplant team if you have a fever or any other signs of infection.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"The home doctor needs it to continue re-vaccinations after the transplant","document":"re-vaccination schedule","source":{"url":"https://www.worcsacute.nhs.uk/leaflets/going-home-after-an-autologous-stem-cell-transplant/","host":"worcsacute.nhs.uk","quote":"Your GP will also be sent a copy of the discharge summary and re-vaccination schedule.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1}},"parsed_details":{"procedure_type":"therapy","fields":{"anesthesia":["local_sedation"],"back_to_work_days":{"min":90,"max":365,"unit":"days","qualifier":"Autologous: desk work in about 3–6 months. Allogeneic: 6–12 months, longer with GVHD. Often part-time at first."},"complication_rate_pct":{"min":50,"max":80,"unit":"percent","qualifier":"Any significant complication in first year; higher with allogeneic transplant."},"contraindications":["Severe uncontrolled active infection","Severe organ dysfunction (heart, lung, liver, kidney) beyond acceptable thresholds","Poor performance status or limited life expectancy from other causes","Active uncontrolled or progressive disease in some settings (relative)","Pregnancy","Lack of suitable donor for allogeneic transplant"],"days_in_clinic":{"min":14,"max":35,"unit":"nights","qualifier":"Autologous: about 2–3 weeks. Allogeneic: about 3–5 weeks until engraftment. Complications extend stay."},"diagnostic_duration_minutes":null,"diagnostic_preparation":null,"diagnostic_referral_needed":null,"diagnostic_result_time_hours":null,"exercise_resume_weeks":{"min":13,"max":52,"unit":"weeks","qualifier":"Light activity early. Strenuous exercise after about 3-6 months (autologous) or 6-12 months (allogeneic), if counts and GVHD allow."},"final_result_months":{"min":6,"max":24,"unit":"months","qualifier":"Engraftment takes about 2–4 weeks. Immune recovery and confirmed remission or disease correction take about 6–24 months."},"fly_home_after_days":{"min":30,"max":100,"unit":"days","qualifier":"Autologous: about 4 weeks after infusion, once counts recover. Allogeneic: usually stay near the center until about day +100."},"follow_up_visits":[{"purpose":"assessment","after":{"min":30,"max":45,"unit":"days","qualifier":"Blood count and complication review after discharge; frequent outpatient visits in the first weeks."},"requirement":"routine"},{"purpose":"assessment","after":{"min":90,"max":100,"unit":"days","qualifier":"Day +100 review of GVHD, infections and immunosuppression taper, mainly after allogeneic transplant."},"requirement":"routine"},{"purpose":"result_review","after":{"min":180,"max":365,"unit":"days","qualifier":"Disease restaging and chimerism or marrow assessment to confirm remission and immune recovery."},"requirement":"routine"},{"purpose":"other","after":{"min":30,"max":180,"unit":"days","qualifier":"Unscheduled review if fever, infection, GVHD signs or graft problems arise."},"requirement":"conditional"}],"indications":["Hematologic malignancies such as leukemia, lymphoma and multiple myeloma","Myelodysplastic syndromes and myeloproliferative neoplasms","Bone marrow failure such as severe aplastic anemia","Thalassemia major and sickle cell disease in selected patients","Primary immunodeficiencies","Relapsed or high-risk disease needing high-dose chemotherapy rescue"],"main_risks":["Serious infections due to prolonged immunosuppression","Graft-versus-host disease (allogeneic)","Graft failure requiring a second transplant","Mucositis, nausea and organ toxicity from conditioning","Bleeding and need for transfusions","Veno-occlusive disease of the liver","Infusion reactions","Infertility and late effects including secondary cancers","Transplant-related mortality"],"pain":"The infusion itself is usually painless, similar to a blood transfusion; discomfort mainly comes from conditioning, mouth sores, nausea and other side effects, managed with supportive care.","preparation":["Comprehensive evaluation of disease status, organ function and infection screening","Stem cell collection by apheresis after mobilization (autologous)","Donor HLA matching and donor clearance (allogeneic)","Central venous catheter placement","Conditioning chemotherapy with or without radiation before infusion","Dental and fertility counseling, and arrangement of caregiver support"],"recovery_timeline":[{"phase":"Conditioning and infusion (day -10 to 0)","description":"Conditioning therapy followed by infusion of stem cells over about 30 minutes to a few hours in hospital.","restrictions":["Inpatient protective isolation"]},{"phase":"Aplasia and engraftment (about days 0-30)","description":"Low blood counts until engraftment, with transfusions, infection prophylaxis and supportive care.","restrictions":["Strict infection precautions","Hospital monitoring"]},{"phase":"Early recovery (about 1-3 months)","description":"Frequent outpatient visits, monitoring for infection and graft-versus-host disease, and gradual strength recovery.","restrictions":["Avoid crowds and sick contacts","Food safety precautions","Stay near transplant center"]},{"phase":"Extended recovery (about 3-12 months)","description":"Gradual immune reconstitution; immunosuppression tapered in allogeneic cases; vaccinations restarted per team schedule; slow return to normal activities.","restrictions":["Ongoing infection precautions","Limited sun exposure"]}],"rehabilitation_days":{"min":60,"max":180,"unit":"days","qualifier":"Daily activities resume in about 1–3 months (autologous) or 3–6 months (allogeneic). Full stamina can take a year."},"result_longevity":"Benefit is often lifelong in patients who stay in remission: most relapses occur within 2 years, and disease-free beyond 2–5 years means high cure chance. In non-malignant disorders, engraftment can be permanent.","revision_rate_pct":{"min":1,"max":5,"unit":"percent","qualifier":"Second transplant for graft failure, mainly after allogeneic transplant."},"scars":"No surgical scar; only a small mark remains at the central venous catheter site.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One stem cell infusion within one admission; a second transplant only for graft failure or relapse."},"stages":[{"code":"conditioning","label":"Conditioning chemotherapy with or without radiation","after":{"min":0,"max":0,"unit":"days","qualifier":"Starts about 5-10 days before infusion; counted here as admission start."}},{"code":"stem_cell_infusion","label":"Stem cell infusion","after":{"min":5,"max":10,"unit":"days","qualifier":"Approximate interval after conditioning starts."}}],"qualifier":"One transplant episode: single infusion after conditioning."},"success":{"metric":"Overall survival after 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weeks."},"initial_assessment_documents":["Bone marrow biopsy and pathology report","Cytogenetic and molecular test results","Previous chemotherapy and response summary","Recent complete blood count and chemistry","PET-CT or staging imaging report","HLA typing and donor details (if available)"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"One 3-5 week admission, then 1-3 months nearby; earlier trip only for evaluation or stem cell collection."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check that you can ask the clinician questions about your treatment during the consultation","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you been able to ask them questions about your treatment?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C2","text":"Check how your aftercare will be coordinated once you return home","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Ensure you're clear about how your aftercare will be coordinated.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C3","text":"Check the qualifications of the medical team treating you","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you checked the qualifications of the medical team treating you?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C4","text":"Check that the clinic provides regular post-transplant check-ups after discharge","scope":"procedure","source":{"url":"https://www.nhs.uk/tests-and-treatments/stem-cell-or-bone-marrow-transplants/recovery/","host":"nhs.uk","quote":"After you leave 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results.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200},"operation_id":800}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1},"technique_details":{"status":"ok","items":[{"id":"autologous-transplant","name":"Autologous transplant","how_it_works":{"text":"Your own stem cells are removed, then returned later","source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/types-of-transplants.html","host":"cancer.org","quote":"Your stem cells are removed from your body and returned to you later.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},"recovery_daily":{"event":"back_to_daily_activities","min":6,"max":8,"unit":"weeks","label":"6–8 weeks","source":{"url":"https://health.ucsd.edu/care/cancer/treatments/blood-and-bone-marrow-transplant/what-to-expect/","host":"health.ucsd.edu","quote":"Most autologous transplant patients begin to return to normal energy levels and activity about six to eight weeks after their BMT.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}},{"id":"allogeneic-transplant","name":"Allogeneic transplant","how_it_works":{"text":"Stem cells come from a donor, related or unrelated to the patient","source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/types-of-transplants.html","host":"cancer.org","quote":"The stem cells in allo transplants come from another person (a donor).","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1}}},"techniques":[{"id":"autologous-transplant","name":"Autologous transplant","how_it_works":{"id":"H1","text":"Your own stem cells are removed, then returned later","source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/types-of-transplants.html","host":"cancer.org","quote":"Your stem cells are removed from your body and returned to you later.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},"recovery_daily":{"event":"back_to_daily_activities","min":6,"max":8,"unit":"weeks","label":"6–8 weeks","source":{"url":"https://health.ucsd.edu/care/cancer/treatments/blood-and-bone-marrow-transplant/what-to-expect/","host":"health.ucsd.edu","quote":"Most autologous transplant patients begin to return to normal energy levels and activity about six to eight weeks after their BMT.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},"suits_whom":"Patients such as those with myeloma or lymphoma who receive their own previously collected stem cells after high-dose chemotherapy.","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Engraftment typically in about 2-3 weeks; shorter admission and lower risk of graft-versus-host disease."},{"id":"allogeneic-transplant","name":"Allogeneic transplant","how_it_works":{"id":"H1","text":"Stem cells come from a donor, related or unrelated to the patient","source":{"url":"https://www.cancer.org/cancer/treatment-types/stem-cell-transplant/types-of-transplants.html","host":"cancer.org","quote":"The stem cells in allo transplants come from another person (a donor).","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Patients with high-risk leukemia, marrow failure or inherited disorders receiving donor cells (matched related, unrelated or haploidentical).","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Longer admission and recovery; risk of graft-versus-host disease and prolonged immunosuppression."}],"alternatives":{"status":"ok","items":[{"id":"A1","text":"Your lymphoma returned after two or more earlier treatments","name":"CAR T-cell therapy","source":{"url":"https://cancer.gov/news-events/cancer-currents-blog/2022/nhl-car-t-cells-belinda-transform-zuma7","host":"cancer.gov","quote":"At the same time, CAR T-cell therapies used after two or more prior treatments have had impressive results.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200},"operation_id":800}],"checked_at":"2026-11-11","next_check_at":"2027-11-11","version":1},"diagnostic":{"status":"not_applicable"},"country":{"why":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-11","next_check_at":"2027-02-09"},"travel":{"status":"ok","items":[{"id":"V1","item":"visa","audience":"uk","volatile":true,"text":"British citizens can visit Israel as tourists without a visa","source":{"url":"https://www.gov.uk/foreign-travel-advice/israel/entry-requirements","host":"gov.uk","quote":"You can visit Israel without a visa as a tourist.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V2","item":"passport_validity","audience":"uk","volatile":true,"text":"To enter Israel, your passport must have an expiry date at least 90 days after the date you arrive","source":{"url":"https://www.gov.uk/foreign-travel-advice/israel/entry-requirements","host":"gov.uk","quote":"To enter Israel or Palestine, your passport must have an ‘expiry date’ at least 90 days after the date you arrive.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V3","item":"arrival_form","audience":"uk","volatile":true,"text":"Visitors must get an Electronic Travel Authorisation (ETA) before arriving in Israel","source":{"url":"https://www.gov.uk/foreign-travel-advice/israel/entry-requirements","host":"gov.uk","quote":"As of 1 January 2025, to visit Israel you will need to get an Electronic Travel Authorisation (ETA) before you arrive.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V4","item":"hospital_payment","audience":"all","volatile":false,"text":"Hospitals in Israel insist on payment and may take legal action to stop you leaving until bills are paid","source":{"url":"https://www.gov.uk/foreign-travel-advice/israel/health","host":"gov.uk","quote":"Hospitals will insist on payment and may take legal action to stop you leaving until bills are paid.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2026-12-11","version":1},"other_countries_with_page":["azerbaijan","china","egypt","germany","greece","india","italy","mexico","republic-of-korea","spain","thailand","turkey","united-kingdom","united-states"]},"often_combined_with":{"status":"missing","reason":"not_collected"},"reviews":{"avg_rating":4.49,"count":190,"scope":"clinic","rating_scale":5,"pros":{"status":"missing","reason":"not_collected"},"cons":{"status":"missing","reason":"not_collected"}},"current":{"seo_text":"<p>Bone marrow transplantation in Israel typically costs from _op_141_price_from_ to _op_141_price_to_. Prices depend on the donor source, patient age, and the required duration of sterile isolation. In the US, similar procedures cost around _price_compare_US_average_ on average. Israel offers savings of around _price_percent_discount_%. Basic costs usually cover evaluation, chemotherapy, the transplant procedure, and initial hospitalization.</p>\n\n<ul>\n<li><strong>Autologous bone marrow transplantation:</strong> _op_176_price_from_ to _op_176_price_to_ using the patient's own stem cells.</li>\n<li><strong>Allogenic transplant (related donor):</strong> _op_177_price_from_ to _op_177_price_to_ for procedures using a family donor.</li>\n<li><strong>Allogenic transplant (unrelated donor):</strong> _op_178_price_from_ to _op_178_price_to_, which accounts for international registry search fees.</li>\n<li><strong>Pediatric protocols:</strong> Specialized care for children often costs more due to higher clinical staffing ratios.</li>\n</ul>\n\n<p><strong>Bookimed Expert Insight:</strong> Choosing Jerusalem can reduce your budget by 15-20% compared to Tel Aviv medical hubs. Shaare Zedek Medical Center offers starting prices around $90,700 for certain protocols. For complex cases, Sheba Medical Center is a world-class leader in advanced CAR-T and TIL therapies. Their \"City of Health\" campus provides specialized care across six hospitals for nearly 2 million patients annually.</p>","faq":[{"q":"What conditions are treated with bone marrow transplants in Israel?","a":"<p>Israeli hematologists treat malignant blood cancers like leukemia, lymphoma, and multiple myeloma, alongside non-malignant disorders including aplastic anemia and immune deficiencies. Specialized centers also address solid tumors like neuroblastoma and medulloblastoma using autologous or allogeneic transplants within JCI-accredited facilities supervised by world-ranked experts.</p> <ul> <li><strong>Malignant conditions:</strong> Treatment for AML, ALL, Hodgkin lymphoma, and refractory multiple myeloma.</li> <li><strong>Non-malignant disorders:</strong> Successful marrow replacement for aplastic anemia and genetic immune deficiencies.</li> <li><strong>Pediatric oncology:</strong> Specialized protocols for rare childhood solid tumors like osteosarcoma and neuroblastoma.</li> <li><strong>Advanced therapies:</strong> Availability of CAR T-cell therapy and haploidentical (half-matched) donor transplants.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli oncology centers like Sheba Medical Center are shifting the standard from invasive hip extractions to peripheral blood stem cell harvesting. This method is less painful for donors and allows for faster engraftment. Our data shows hospitals here lead in haploidentical transplants, which drastically broadens donor options for patients without a perfect family match.</p> <p><strong>Patient Consensus:</strong> Patients emphasize the importance of understanding the isolation phase, which typically lasts 3 weeks. Many report choosing Israel specifically for their high success rates in treating sickle cell disease and complex myeloma cases.</p>"},{"q":"What is the procedure for an allogeneic transplant (using a donor)?","a":"<p>An allogeneic transplant in Israel involves replacing damaged marrow with healthy donor stem cells through a structured surgical and medical protocol. The process includes HLA typing for donor compatibility, intensive conditioning via chemotherapy, and a 10-to-20 minute intravenous infusion followed by a 21-day engraftment period in strict isolation.</p> <ul> <li><strong>Donor matching:</strong> Surgeons verify 8, 10, or 12 HLA markers to minimize graft-versus-host disease (GVHD) risks.</li> <li><strong>Cell collection:</strong> Donors spend 4–6 hours undergoing apheresis after 4 days of growth factor stimulation.</li> <li><strong>Conditioning phase:</strong> Recipient immune systems are suppressed through intensive chemotherapy over 5 to 10 days.</li> <li><strong>Hospital recovery:</strong> Patients remain in sterile isolation for approximately 30 days during the engraftment phase.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli centers like Rambam and Sheba offer specialized pediatric protocols that integrate advanced cellular immunotherapies. Data shows clinics here maintain high success rates by performing over 2,000 procedures. Many packages for allogeneic transplants automatically include 30 hospital days, which is vital for managing early post-transplant complications.</p> <p><strong>Patient Consensus:</strong> Expect 3 weeks of strict isolation with no outside food or plants. Patients emphasize that a 24/7 caregiver is essential during the 5-week period of flu-like symptoms.</p>"},{"q":"Why choose Israel for a bone marrow transplant?","a":"<p>Israel is a premier destination for bone marrow transplants, offering advanced CAR-T therapies and high success rates for leukemia and lymphoma. Patients benefit from JCI-accredited facilities like Sheba Medical Center, which provides world-class pediatric protocols and access to extensive international donor registries at a lower cost.</p> <ul> <li><strong>Cost savings:</strong> Procedures cost _op_141_price_from_ to _op_141_price_to_, saving approximately _price_percent_discount_% compared to US prices.</li> <li><strong>Expert surgical volume:</strong> Specialists like Polina Stepensky at Hadassah Medical Center have performed 3,500+ transplants.</li> <li><strong>Advanced technology:</strong> Sheba Medical Center features on-site CAR-T manufacturing and GMP-certified biotherapy laboratories.</li> <li><strong>Pediatric specialization:</strong> Dana Dwek Children's Hospital holds specific accreditation from the European Society for Blood and Marrow Transplantation.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> While many countries offer standard transplants, Israel leads in cellular immunotherapy integration. Sheba Medical Center is ranked 7th worldwide by Newsweek and hosts 200+ Forbes-listed top doctors. This expertise allows Israeli clinics to treat high-risk cases that other international centers might decline.</p> <p><strong>Patient Consensus:</strong> Patients value the intensive 30-day isolation protocols and highly specialized nursing care essential for immune system recovery. The emotional journey is supported by multidisciplinary teams who manage complex HLA donor matching through global registries.</p>"},{"q":"How does the hospital handle finding a donor?","a":"<p>Israeli hospitals identify bone marrow donors through an organized protocol involving initial family HLA screening followed by access to global registries. Specialists at Joint Commission International (JCI) accredited centers utilize advanced HLA typing to match recipients with siblings or unrelated volunteers across international databases.</p> <ul> <li><strong>Sibling screening:</strong> Medical teams first test biological siblings who share a 25% match probability.</li> <li><strong>Registry access:</strong> Coordinators search national and international volunteer databases if no related donor exists.</li> <li><strong>HLA typing:</strong> Doctors use high-resolution DNA testing to ensure compatible human leukocyte antigen markers.</li> <li><strong>Medical clearance:</strong> Identified donors undergo rigorous infection screenings and health evaluations before the harvest.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli centers like Hadassah Medical Center provide a significant advantage by housing their own public bone marrow registries onsite. This integration speeds up the search process compared to facilities that must rely solely on external third-party networks. This direct access is a key reason why specialists like Dr. Polina Stepensky have successfully performed over 3,500 transplants.</p> <p><strong>Patient Consensus:</strong> Patients emphasize starting with sibling testing immediately as it remains the fastest route to transplantation. Most find relief knowing modern collection usually involves a blood-filtering process similar to dialysis rather than hip surgery.</p>"},{"q":"Why is Israel a top destination for neurosurgery?","a":"<p>Israel is a premier neurosurgery hub due to its fusion of high-density medical innovation and elite surgical expertise. Top facilities like Sheba Medical Center integrate AI-guided navigation and real-time intraoperative MRI. Specialized centers report 98% success rates for complex procedures including awake craniotomy and movement disorder treatments.</p> <ul> <li><strong>Advanced technology:</strong> Clinics utilize MRI-guided focused ultrasound (MRgFUS) and robotic systems for incisions.</li> <li><strong>Surgical expertise:</strong> Surgeons like Dr. Zvi Ram lead international associations with 25+ years experience.</li> <li><strong>Rapid access:</strong> International patients typically schedule complex brain or spine surgeries within 2–4 weeks.</li> <li><strong>Accredited care:</strong> Major centers like Sourasky (Ichilov) and Assuta hold JCI accreditation for safety.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data shows a clear divide between public and private options in Israel. Private centers like Assuta Medical Center perform over 92,000 operations annually and allow patients to select their specific lead surgeon. This is a vital advantage for complex cases where a specific expert like Dr. Eli Ashkenazi is preferred for his 1,000+ spine surgery record.</p> <p><strong>Patient Consensus:</strong> Patients emphasize bringing original imaging on a USB for local review to streamline the surgical plan. They also note that private packages often include hotel coordination and airport transfers, making the logistics much smoother.</p>"},{"q":"What types of neurosurgical conditions are treated in Israel?","a":"<p>Israeli neurosurgeons treat a full spectrum of conditions ranging from brain and spinal tumors to complex functional disorders. Specialized centers utilize advanced technologies like Gamma Knife, deep brain stimulation, and intraoperative MRI to manage epilepsy, Parkinson disease, and cerebrovascular pathologies with high precision.</p> <ul> <li><strong>Oncological conditions:</strong> Treatment for gliomas, meningiomas, and pituitary tumors using skull base resection.</li> <li><strong>Functional disorders:</strong> Management of Parkinson disease and essential tremors via deep brain stimulation.</li> <li><strong>Spinal pathologies:</strong> Correction of scoliosis, herniated discs, and spinal tumors using robotic systems.</li> <li><strong>Cerebrovascular care:</strong> Surgical repair of brain aneurysms and arteriovenous malformations with endovascular interventions.</li> <li><strong>Pediatric neurosurgery:</strong> Specialized care for hydrocephalus and congenital anomalies at dedicated children centers.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli hospitals often combine specialties to handle complex cases. At Sourasky Medical Center, neurosurgeons like Dr. Zvi Lidar bridge neurosurgery and orthopedics for spinal care. This multidisciplinary approach allows clinics to perform 34,000+ operations annually. Choosing a facility with this crossover expertise often leads to more comprehensive treatment plans for degenerative diseases.</p> <p><strong>Patient Consensus:</strong> Patients value the ability to access specialized treatments like fluorescence-guided surgery for tumors which are often unavailable elsewhere. Many note that the staff is fluent in English and provides clear communication through teleconsultations before traveling.</p>"},{"q":"Which hospitals in Israel are best known for neurosurgery?","a":"<p>Israel is home to world-renowned neurosurgery centers like Sourasky Medical Center, Sheba Medical Center, and Hadassah Medical Center. These facilities are globally ranked for treating complex brain tumors, spinal disorders, and movement diseases. They utilize advanced technologies like Gamma Knife, robotic systems, and intra-operative MRI.</p> <ul> <li><strong>Sourasky (Ichilov):</strong> Performs 2,500+ neurosurgical operations yearly with a 98% success rate in Tel Aviv.</li> <li><strong>Sheba Medical Center:</strong> Ranked among the world's top 10 hospitals. It treats 1.9 million patients annually.</li> <li><strong>Hadassah Medical Center:</strong> A Nobel Peace Prize nominee. It leads in pediatric neurosurgery and gene-based therapies.</li> <li><strong>Assuta Medical Center:</strong> Israel's largest private facility. It specializes in minimally invasive spine and brain surgeries.</li> <li><strong>Schneider Children's:</strong> The primary center for pediatric neurosurgery. It treats 275,000 children every year.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Our data shows that while most patients focus on Tel Aviv, Rambam Medical Center in Haifa offers unique expertise in neuro-trauma. It operates a specialized neuro-ICU and serves nearly 1 million patients annually. This makes it an essential choice for complex post-trauma brain surgeries that requires intensive recovery support.</p> <p><strong>Patient Consensus:</strong> Patients note it is important to start consultations early. They often highlight that the precision and follow-up care for complex brain tumors exceeded their expectations. One patient emphasized how quickly they could connect with top professors for second opinions during critical neurosurgical cases.</p>"},{"q":"Who are Israel’s leading neurosurgeons?","a":"<p>Israel's leading neurosurgeons include Prof. Zvi Ram, Prof. Shlomi Constantini, and Prof. Itzhak Fried at Sourasky Medical Center. These specialists hold leadership roles in the European Association of Neurosurgical Societies (EANS) and the World Society for Stereotactic and Functional Neurosurgery (WSSFN). They utilize advanced intraoperative mapping and robotic systems.</p> <ul> <li><strong>Prof. Zvi Ram:</strong> Expert in minimally invasive brain tumor surgery and gene-based oncology therapies.</li> <li><strong>Prof. Shlomi Constantini:</strong> Specializes in complex pediatric neuro-endoscopy and brain tumor microsurgery.</li> <li><strong>Prof. Itzhak Fried:</strong> Authority on epilepsy surgery, functional brain mapping, and deep brain stimulation.</li> <li><strong>Dr. Eli Ashkenazi:</strong> Leading spine surgeon at Assuta, specializing in the innovative TOPS system.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data from Sourasky and Sheba indicates a strong correlation between high surgical volumes and patient safety. For example, Sourasky performs 34,000+ operations annually with a 90% oncology success rate. Patients seeking complex tumor removals should prioritize centers like these where surgeons perform hundreds of specific cases each year.</p> <p><strong>Patient Consensus:</strong> Patients emphasize the importance of finding a surgeon who specializes specifically in your condition rather than a generalist. Many note that high-volume centers provide better access to English-speaking staff and coordinated care for international visitors.</p>"},{"q":"What are the admission requirements for international neurosurgery patients?","a":"<p>International neurosurgery patients in Israel must provide comprehensive medical records including recent MRI or CT scans translated into English. Admission requires a clinical review by specialists to confirm treatment feasibility. Hospitals often mandate full advance payment or a significant deposit before confirming surgery dates or issuing visa support letters.</p> <ul> <li><strong>Medical documentation:</strong> Submit detailed English-translated reports and imaging for clinical review within 48 hours.</li> <li><strong>Financial clearance:</strong> Provide proof of funds for approximately _price_from_ to _price_to_ for treatment.</li> <li><strong>Visa support:</strong> Clinics like Sourasky Medical Center (Ichilov) issue official letters for medical B-2 visas.</li> <li><strong>Consultation phase:</strong> Initial assessment often occurs via online consultation with surgeons like Dr. Strauss Ido.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data shows that top Israeli facilities like Sheba Medical Center and Hadassah Medical Center handle massive patient volumes, exceeding 1,000,000 people annually. This high demand means clinics prioritize complex or rare cases over routine procedures. Patients with unique or high-risk conditions often receive faster admission approval than those seeking standard treatments available elsewhere.</p> <p><strong>Patient Consensus:</strong> Patients note that having all imaging results ready in English is essential for quick scheduling. Many emphasize that while the medical care is excellent, coordinating around Shabbat closures is necessary to avoid unexpected diagnostic delays.</p>"},{"q":"How long will I need to stay in Israel for neurosurgery and follow-up?","a":"<p>A standard stay for neurosurgery in Israel ranges from 10 to 14 days for uncomplicated cases. Patients undergoing complex procedures like brain tumor removal or deep brain stimulation often require 4 to 6 weeks. This timeline covers pre-operative diagnostics, the surgical procedure, and essential post-operative monitoring.</p> <ul> <li><strong>Hospitalization duration:</strong> Minimally invasive procedures require 1–3 days. Regular craniotomies average 3–10 days.</li> <li><strong>Local recovery:</strong> Stay in Israel for 7–14 days post-discharge for mandatory follow-up checks.</li> <li><strong>Flight safety:</strong> Surgeons recommend waiting 4–6 weeks before flying to stabilize internal head pressure.</li> <li><strong>Follow-up schedule:</strong> In-person clinical reviews typically occur at days 3, 7, and 14 post-surgery.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data from Sourasky Medical Center shows they treat over 400,000 patients annually with high success rates. Clinics with such high volumes, like Hadassah or Assuta, often have streamlined discharge protocols. This helps international patients transition to hotel-based recovery faster while maintaining access to top specialists.</p> <p><strong>Patient Consensus:</strong> Patients note it is vital not to rush home too early. Some travelers extended their stay to 3 weeks due to swelling or to ensure they received final surgeon clearance before flying.</p>"},{"q":"What advanced technologies make Israeli neurosurgery minimally invasive?","a":"<p>Israeli neurosurgery uses robotic guidance, real-time 3D imaging, and incisionless technologies to minimize physical trauma. Systems like Mazor Robotics provide sub-millimeter precision for spine implants. MRI-guided focused ultrasound (MRgFUS) treats tremors without incisions. These advanced tools ensure high accuracy and reduce recovery times.</p> <ul> <li><strong>Robotic systems:</strong> Mazor and ROSA robotics enable precise instrument placement through tiny incisions.</li> <li><strong>Incisionless ultrasound:</strong> MRgFUS uses high-intensity sound waves to treat brain tissue without anesthesia.</li> <li><strong>Digital navigation:</strong> Intraoperative MRI and 3D mapping allow surgeons to verify results in real-time.</li> <li><strong>Advanced endoscopy:</strong> Transnasal and trans-orbital approaches remove tumors without traditional skull-opening craniotomies.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli clinics like Sourasky or Hadassah integrate proprietary Israeli-born technologies like Surgical Theater before they hit global markets. Our data shows these centers often use VR flight-through models for pre-surgical planning. This allows surgeons to rehearse complex cases, which is a key factor in their 90% success rates.</p> <p><strong>Patient Consensus:</strong> Patients note that technologies like the Gamma Knife allowed them to return home in days rather than weeks. Many move from traditional 10cm incisions to cuts under 2cm when using robotic-assisted systems.</p>"},{"q":"Why is Israel considered a top destination for neurosurgery?","a":"<p>Israel is a global leader in neurosurgery due to its integration of proprietary medical innovations and internationally trained specialists. High-capacity centers like Sourasky Medical Center (Ichilov) perform over 34,000 annual surgeries. Patients access advanced techniques like awake craniotomy and MR-guided focused ultrasound.</p> <ul> <li><strong>Advanced technology:</strong> Facilities use CyberKnife, Gamma Knife, and robotic systems for precision.</li> <li><strong>Expert credentials:</strong> Specialists like Dr. Zvi Ram hold leadership roles in European neurosurgical societies.</li> <li><strong>Global training:</strong> Most senior neurosurgeons completed fellowships at premier United States and European institutions.</li> <li><strong>Specialized departments:</strong> Centers feature niche units for pediatric neurosurgery, skull base, and functional disorders.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli neurosurgery stands out because of the high concentration of dually certified experts. Many top surgeons, such as Dr. Zvi Lidar, are certified to practice in both Israel and the USA. This ensures that patients receive American-standard surgical care while staying in Tel Aviv or Jerusalem. Our data shows that private centers like Assuta offer significantly faster access to these specific specialists compared to the public system.</p> <p><strong>Patient Consensus:</strong> Patients note it is important to confirm a surgeon's specific volume of cases for your exact condition. They also value the ability to get expert second opinions quickly through online consultations with world-renowned professors.</p>"},{"q":"Which hospitals are ranked among the best for neurosurgery in Israel?","a":"<p>Sheba Medical Center and Sourasky Medical Center (Ichilov) are among the best neurosurgery hospitals in Israel. These JCI-accredited facilities perform thousands of operations annually. They utilize advanced technologies like CyberKnife and intraoperative MRI to treat complex brain tumors and cerebrovascular lesions.</p> <ul> <li><strong>Sheba Medical Center:</strong> Ranked among the top 10 world hospitals by Newsweek magazine.</li> <li><strong>Sourasky (Ichilov):</strong> Reports a 98% success rate and performs 2,500+ neurosurgical operations annually.</li> <li><strong>Hadassah Medical Center:</strong> Known for pioneering endoscopic techniques and integrated advanced research programs.</li> <li><strong>Assuta Medical Center:</strong> Israel largest private facility specializing in minimally invasive spine procedures.</li> <li><strong>Rambam Medical Center:</strong> Employs Nobel Prize laureates and serves as a major referral center.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Our data shows that top Israeli centers like Sourasky and Hadassah perform over 40,000 total operations yearly. This high volume allows surgeons to maintain a 90% success rate even in complex oncology cases. Patients seeking robotic spine surgery or deep brain stimulation should focus on these high-capacity municipal centers for the most experienced teams.</p> <p><strong>Patient Consensus:</strong> Patients appreciate that some hospitals quickly coordinate consultations even during regional strikes. Families of pediatric patients especially value surgeons trained at prestigious international institutions.</p>"},{"q":"Who are the leading neurosurgeons in Israel?","a":"<p>Israel's leading neurosurgeons include Professor Zvi Ram, Professor Shlomi Constantini, and Professor Itzhak Fried at Sourasky Medical Center. These experts specialize in awake craniotomy, pediatric brain tumors, and functional mapping. Most hold JCI accreditation and international fellowships from institutions like Johns Hopkins and Yale.</p> <ul> <li><strong>Brain tumors:</strong> Professor Zvi Ram specializes in image-guided microsurgery and complex brain mapping techniques.</li> <li><strong>Pediatric expertise:</strong> Professor Shlomi Constantini leads pediatric neurosurgery, focusing on endoscopic treatments and malformations.</li> <li><strong>Functional surgery:</strong> Professor Itzhak Fried is a global authority on epilepsy and deep brain stimulation.</li> <li><strong>Spine specialists:</strong> Dr. Zvi Lidar and Dr. Eli Ashkenazi focus on minimally invasive spinal oncology.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data shows that top-tier Israeli neurosurgeons, such as those at Sourasky Medical Center, often hold dual board certifications in Israel and the US. This unique crossover ensures patients receive American-standard protocols. These specialists typically manage over 34,000 annual operations, providing high-volume clinical experience that smaller private clinics cannot match.</p> <p><strong>Patient Consensus:</strong> Patients note that highly qualified doctors like Professor Shlomo Constantini provide satisfactory answers quickly. People emphasize that outcomes often depend on the hospital’s integrated resources rather than just a doctor's prestige.</p>"},{"q":"What neurosurgical conditions and sub-specialties are treated in Israel?","a":"<p>Israel is a global leader in neurosurgery, treating complex brain and spinal conditions using robotic-assisted and minimally invasive techniques. Highly specialized units at JCI-accredited centers like Sourasky Medical Center (Ichilov) and Hadassah Medical Center focus on neuro-oncology, pediatric neurosurgery, and functional procedures.</p> <ul> <li><strong>Neuro-oncology:</strong> Treating glioblastoma, meningioma, and skull base tumors with 90% success rates.</li> <li><strong>Functional neurosurgery:</strong> Performing deep brain stimulation (DBS) for Parkinson’s and drug-resistant epilepsy.</li> <li><strong>Pediatric specialty:</strong> Specialized care for congenital defects and childhood tumors at Schneider Children’s.</li> <li><strong>Spine surgery:</strong> Utilizing Mazor X robotic systems for scoliosis and herniated disc correction.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Israeli neurosurgical departments often function as rapid-response hubs for international patients. Data shows that large centers like Sourasky, which serves 1,800,000 patients annually, can organize expert video consultations in a very short time. This speed is critical for neuro-oncology cases where starting treatment a few days earlier significantly impacts outcomes.</p> <p><strong>Patient Consensus:</strong> Patients note that Israeli teams often accept high-risk cases that other hospitals decline. They emphasize the importance of using local coordinators to manage travel logistics or potential local disruptions during their two-week stay.</p>"},{"q":"What documentation do international patients need before traveling to Israel for neurosurgery?","a":"<p>International patients traveling to Israel for neurosurgery require a valid passport, an entry permit or medical visa, and a formal hospital invitation. You must provide recent MRI or CT scans in DICOM format and detailed medical summaries. Proof of private health insurance and financial stability are also mandatory for border entry.</p> <ul> <li><strong>Travel authorization:</strong> Most visa-exempt travelers now need an approved ETA-IL before departure.</li> <li><strong>Hospital invitation:</strong> A signed letter from facilities like Sourasky Medical Center is required.</li> <li><strong>Medical records:</strong> Provide updated summaries of diagnoses, medications, and previous neurological treatments.</li> <li><strong>Imaging files:</strong> Digital copies of scans are essential for planning complex brain surgeries.</li> <li><strong>Legal consent:</strong> Notarized power of attorney is required for patients under 18 years old.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Our data shows that top neurosurgeons at Hadassah Medical Center and Sourasky often request records 4–6 weeks before arrival. Submitting these early prevents appointment shifts. High-volume centers with over 30,000 annual operations have dedicated portals for secure DICOM file uploads. Using these ensures your surgeon reviews high-quality images before you land in Tel Aviv.</p> <p><strong>Patient Consensus:</strong> Patients emphasize bringing physical copies and digital backups of all scans on a USB drive. They also note that private insurance needs pre-authorization specifically for neurosurgery to avoid payment delays at the clinic.</p>"}],"h2":[{"text":"Как это работает","kind":"content"},{"text":"Какая цена пересадки костного мозга в Израиле?","kind":"content"},{"text":"Предложения по пересадке костного мозга в Израиле — ноябрь 2026","kind":"content"},{"text":"Лучшие клиники по пересадке костного мозга в Израиле — 13 проверенных вариантов с ценами","kind":"content"},{"text":"Пересадка костного мозга в Израиле: план поездки","kind":"content"},{"text":"Лучшие специалисты по пересадке костного мозга в Израиле — 26 докторов с отзывами и ценами","kind":"content"},{"text":"Видеоистории пациентов Bookimed","kind":"content"},{"text":"Отзывы о Bookimed: узнайте о реальном опыте пациентов","kind":"content"},{"text":"Полезные статьи","kind":"content"},{"text":"Поделитесь этим материалом","kind":"content"},{"text":"Все, что вам нужно знать о пересадке костного мозга в Израиле","kind":"content"},{"text":"Что важно знать о пересадке костного мозга (ТКМ) в Израиле?","kind":"content"},{"text":"Как выбрать клинику и записаться на консультацию?","kind":"content"},{"text":"Из каких этапов состоит трансплантация костного мозга в Израиле?","kind":"content"},{"text":"Что влияет на стоимость пересадки костного мозга в Израиле?","kind":"content"},{"text":"Что включает цена на пересадку костного мозга в Израиле?","kind":"content"},{"text":"FAQ по пересадке костного мозга в Израиле","kind":"content"},{"text":"Получить бесплатную консультацию","kind":"content"}]},"placeholders":{"price_from":"{{price_from}}","clinics_count":"{{clinics_count}}","cities_count":"{{cities_count}}","savings_pct":"{{savings_pct}}","data_date":"{{data_date}}"},"legal":{"restricted_markets":{"status":"missing","reason":"not_collected"}},"conflicts":[{"field":"price.avg","chosen":"offers","offers":164000,"price_from":79000,"ratio":2.08,"threshold":2}]}