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higher.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"The child has favorable tumor biology without signs or symptoms","name":"Observation and supportive care","source":{"url":"https://www.cancer.gov/types/neuroblastoma/patient/neuroblastoma-treatment-pdq","host":"cancer.gov","quote":"observation and supportive care for children who have favorable tumor biology and do not have signs or symptoms","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"technique_details":{"status":"ok","items":[{"id":"multiagent-chemotherapy","name":"Multiagent chemotherapy with surgery","how_it_works":{"text":"Chemotherapy is given first, and surgery removes the primary tumor when possible","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/high-risk-neuroblastoma-tandem-transplant","host":"cancer.gov","quote":"Treatment of patients with high-risk neuroblastoma begins with induction therapy, which involves multi-drug chemotherapy regimens and, when possible, surgical removal of the primary tumor.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"high-dose-chemotherapy","name":"High-dose chemotherapy with autologous stem cell rescue, radiotherapy and anti-GD2 immunotherapy","how_it_works":{"text":"High-dose chemotherapy is followed by infusion of stored blood stem cells","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/high-risk-neuroblastoma-tandem-transplant","host":"cancer.gov","quote":"That is followed by consolidation therapy, which involves administration of very high-dose chemotherapy and infusion of the patient’s own stored blood stem cells, known as an autologous transplant.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"mibg-radionuclide-therapy","name":"MIBG radionuclide therapy","how_it_works":{"text":"MIBG delivers radiation directly to cancer cells","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/high-risk-neuroblastoma-tandem-transplant","host":"cancer.gov","quote":"I 131 MIBG—which delivers radiation directly to cancer cells—is being tested as part of induction therapy.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1}}},"techniques":[{"id":"multiagent-chemotherapy","name":"Multiagent chemotherapy with surgery","how_it_works":{"id":"H1","text":"Chemotherapy is given first, and surgery removes the primary tumor when possible","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/high-risk-neuroblastoma-tandem-transplant","host":"cancer.gov","quote":"Treatment of patients with high-risk neuroblastoma begins with induction therapy, which involves multi-drug chemotherapy regimens and, when possible, surgical removal of the primary tumor.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Intermediate-risk disease","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Several months of cycles; surgery recovery 1-3 weeks."},{"id":"high-dose-chemotherapy","name":"High-dose chemotherapy with autologous stem cell rescue, radiotherapy and anti-GD2 immunotherapy","how_it_works":{"id":"H1","text":"High-dose chemotherapy is followed by infusion of stored blood stem cells","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/high-risk-neuroblastoma-tandem-transplant","host":"cancer.gov","quote":"That is followed by consolidation therapy, which involves administration of very high-dose chemotherapy and infusion of the patient’s own stored blood stem cells, known as an autologous transplant.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"High-risk disease","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Treatment lasts about 12-18 months."},{"id":"mibg-radionuclide-therapy","name":"MIBG radionuclide therapy","how_it_works":{"id":"H1","text":"MIBG delivers radiation directly to cancer cells","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/high-risk-neuroblastoma-tandem-transplant","host":"cancer.gov","quote":"I 131 MIBG—which delivers radiation directly to cancer cells—is being tested as part of induction therapy.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Relapsed or refractory MIBG-avid disease","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Short isolation after dosing; blood counts monitored."}],"alternatives":{"status":"ok","items":[{"id":"A1","text":"The child has favorable tumor biology without signs or symptoms","name":"Observation and supportive care","source":{"url":"https://www.cancer.gov/types/neuroblastoma/patient/neuroblastoma-treatment-pdq","host":"cancer.gov","quote":"observation and supportive care for children who have favorable tumor biology and do not have signs or symptoms","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"diagnostic":{"status":"not_applicable"},"country":{"why":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-11","next_check_at":"2027-02-09"},"travel":{"status":"ok","items":[{"id":"V1","item":"passport_validity","audience":"uk","volatile":true,"text":"The passport must have an expiry date at least 3 months after you plan to leave the Schengen area","source":{"url":"https://www.gov.uk/foreign-travel-advice/spain/entry-requirements","host":"gov.uk","quote":"have an ‘expiry date’ at least 3 months after the day you plan to leave the Schengen area (the expiry date does not need to be within 10 years of the date of issue)","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V2","item":"medicines","audience":"all","volatile":false,"text":"Carry prescription medication in its original packaging, along with your doctor's prescription","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Spain.html","host":"travel.state.gov","quote":"Always carry your prescription medication in original packaging, along with your doctor’s prescription.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V3","item":"prescriptions","audience":"us","volatile":false,"text":"Medications that require a prescription in the United States also require a local doctor's prescription in Spain","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Spain.html","host":"travel.state.gov","quote":"Medications requiring prescriptions in the United States also require a local doctor’s prescription in Spain.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V4","item":"ghic","audience":"uk","volatile":false,"text":"A GHIC or EHIC is needed to get medically necessary state healthcare in Spain","source":{"url":"https://www.gov.uk/foreign-travel-advice/spain/health","host":"gov.uk","quote":"To get medically necessary state healthcare in Spain, you need a Global Health Insurance Card ( GHIC ) or a European Health Insurance Card ( EHIC ).","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V5","item":"hospital_payment","audience":"all","volatile":false,"text":"Private hospitals usually require payment or proof of insurance or funds before admitting a patient","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Spain.html","host":"travel.state.gov","quote":"Private hospitals usually require payment or proof insurance or funds before admitting a patient.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V6","item":"emergency_number","audience":"all","volatile":false,"text":"Dial 112 and ask for an ambulance","source":{"url":"https://www.gov.uk/foreign-travel-advice/spain/health","host":"gov.uk","quote":"Dial 112 and ask for an ambulance.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2026-12-11","version":1},"other_countries_with_page":["austria","egypt","germany","india","israel","republic-of-korea","thailand","turkey"]},"often_combined_with":{"status":"missing","reason":"not_collected"},"reviews":{"avg_rating":4.72,"count":47,"scope":"clinic","rating_scale":5,"pros":{"status":"missing","reason":"not_collected"},"cons":{"status":"missing","reason":"not_collected"}},"current":{"seo_text":"<p>Complex treatment of neuroblastoma in Spain typically costs from _op_409_price_from_ to _op_409_price_to_. The total price depends on the specific protocol, tumor stage, and required technologies. In the US, similar procedures cost around _price_compare_US_average_ on average. Patients save around _price_percent_discount_% compared to US prices. This treatment usually includes surgery, intensive chemotherapy, and specialized pediatric nursing care.</p>\n\n<ul>\n<li><strong>Advanced radiation:</strong> Proton therapy typically costs 50-60% more than standard radiotherapy sessions.</li>\n<li><strong>Targeted MIBG therapy:</strong> This specialized molecular treatment often adds significant costs to the baseline.</li>\n<li><strong>Stem cell transplant:</strong> High-dose chemotherapy with autologous rescue increases the total budget significantly.</li>\n<li><strong>City variations:</strong> Major medical hubs for this treatment include Barcelona and Madrid.</li>\n</ul>\n\n<p><strong>Bookimed Expert Insight:</strong> Choosing a specialized pediatric center offers the best clinical value for complex cases. SJD Barcelona Children's Hospital is among the top three pediatric institutions in Europe. It performs approximately 14,000 operations annually with a dedicated molecular medicine laboratory. Expert oncologists like Lopez Ibor in Madrid bring over 20 years of experience. These centers provide high-intensity protocols that are often unavailable at smaller regional clinics.</p>","faq":[{"q":"What is complex neuroblastoma treatment?","a":"<p>Complex neuroblastoma treatment consists of a multi-phase regimen for high-risk, metastatic, or recurrent cases. This intensive protocol spans 12 to 18 months, combining induction chemotherapy, surgical resection, myeloablative consolidation with stem cell rescue, and maintenance immunotherapy to target residual microscopic disease.</p> <ul> <li><strong>Induction phase:</strong> Intense rotating chemotherapy cycles shrink primary tumors and treat metastatic sites.</li> <li><strong>Surgical debulking:</strong> Specialized surgeons perform intricate resections, often protecting the aorta and vital organs.</li> <li><strong>Consolidation phase:</strong> High-dose chemotherapy followed by autologous stem cell transplant clears lingering cancer cells.</li> <li><strong>Maintenance therapy:</strong> Anti-GD2 immunotherapy and oral retinoids train the immune system to prevent relapse.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Spain hosts world-leading pediatric oncology hubs like SJD Barcelona Children's Hospital, ranked among Europe's top three. Data show these centers offer molecular medicine labs that refine treatment protocols in real-time. This specialized focus often results in costs around _price_percent_discount_% lower than US averages for identical advanced regimens.</p> <p><strong>Patient Consensus:</strong> Families emphasize that treatment is a long-distance marathon where plans shift based on pathology results. While side effects from immunotherapy are intense, centralized care in specialized pediatric hospitals simplifies the complex coordination required.</p>"},{"q":"Which Spanish hospitals specialize in complex neuroblastoma care?","a":"<p>Spain hosts globally recognized pediatric oncology centers like SJD Barcelona Children's Hospital and Hospital Universitario HM Montepríncipe. These facilities provide advanced anti-GD2 immunotherapy, molecular profiling, and precision surgery. Specialized teams in Madrid and Barcelona manage high-risk cases using low-toxicity protocols to improve survival rates.</p> <ul> <li><strong>SJD Barcelona:</strong> Features a dedicated pediatric cancer center treating 450,000 patients annually with innovative methods.</li> <li><strong>Dr. Lopez Ibor:</strong> Leads HM Montepríncipe hematology-oncology unit with extensive University of Maryland specialized training.</li> <li><strong>Hospital Ruber Internacional:</strong> Provides JCI-accredited care in Madrid for international patients requiring complex diagnostic imaging.</li> <li><strong>Treatment complexity:</strong> Centers integrate surgery, ICU, and stem cell transplant capabilities for refractory cases.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> While many general hospitals have pediatric wards, SJD Barcelona is one of only three specialized pediatric-only giants in Europe. This focus is critical because their surgeons perform 14,000 operations yearly. Such high volume ensures they handle rare tumor resections near major vessels with higher precision than general surgeons.</p> <p><strong>Patient Consensus:</strong> Families emphasize choosing major tertiary children's hospitals over general wards for complex resections. They highlight that access to in-house nuclear medicine and MIBG imaging is vital for coordinating effective high-risk neuroblastoma care.</p>"},{"q":"Why is Spain considered a leading destination for complex neuroblastoma treatment?","a":"<p>Spain is a global leader in neuroblastoma care due to its pioneering anti-GD2 immunotherapy and high survival rates. Institutions like SJD Barcelona Children’s Hospital achieve 90% survival for high-risk cases while offering low-toxicity protocols. Spanish specialists provide advanced surgical precision and access to cutting-edge clinical trials.</p> <ul> <li><strong>Survival rates:</strong> Spanish centers exceed global benchmarks with 91.6% 3-year survival for high-risk patients.</li> <li><strong>Innovative immunotherapy:</strong> Targeted Naxitamab treatment trains the immune system to destroy cancer cells effectively.</li> <li><strong>Outpatient care:</strong> Approximately 95% of immunotherapy infusions are performed without requiring overnight hospital stays.</li> <li><strong>Reduced toxicity:</strong> Protocols prioritize targeted therapies over intensive transplants to minimize long-term organ damage.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> While many countries rely on aggressive transplants, Spain’s SJD Barcelona Children’s Hospital has successfully phased them out for many patients. This approach significantly reduces side effects like hearing loss or kidney issues common in traditional care. Since Spain pioneered these low-toxicity infusion protocols early, their nursing teams are exceptionally skilled at managing pain during the process.</p> <p><strong>Patient Consensus:</strong> Families value the highly coordinated care where surgeons and radiologists collaborate under one roof. They often highlight the speed of admission and how clinical teams provide clear, detailed explanations during stressful periods.</p>"},{"q":"What advanced immunotherapies and targeted agents are currently available in Spain for neuroblastoma?","a":"<p>Spain offers elite neuroblastoma therapies including anti-GD2 immunotherapies like Dinutuximab Beta and Naxitamab, alongside targeted ALK inhibitors. Specialized centers like SJD Barcelona Children's Hospital provide these through standard protocols or early-access registries. Molecular profiling determines eligibility for third-generation agents like Lorlatinib for high-risk cases.</p> <ul> <li><strong>Anti-GD2 immunotherapy:</strong> Dinutuximab Beta serves as the European standard for maintenance and relapse.</li> <li><strong>Specialized antibodies:</strong> Naxitamab targets bone marrow relapses, often administered at SJD Barcelona.</li> <li><strong>ALK inhibitors:</strong> Lorlatinib and Crizotinib treat mutated tumors with high central nervous system penetration.</li> <li><strong>Maintenance therapy:</strong> Eflornithine is available through foreign medication channels to reduce relapse risks.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Spain ranks among the top two global destinations for complex pediatric oncology on our platform. SJD Barcelona Children's Hospital treats 450,000 patients annually and pioneered Naxitamab use globally. This massive patient volume ensures surgeons and oncologists manage rare mutations more frequently than most regional hospitals.</p> <p><strong>Patient Consensus:</strong> Families emphasize that while anti-GD2 therapies are effective, they often require inpatient monitoring for pain. Molecular profiling is vital to unlock targeted options like ALK inhibitors.</p>"}],"h2":[{"text":"Как это работает","kind":"content"},{"text":"Какая цена комплексного лечения нейробластомы в Испании?","kind":"content"},{"text":"Лучшие клиники по Комплексное лечение нейробластомы в Испании — 2 проверенных варианта с ценами","kind":"content"},{"text":"Обзор процедуры Комплексное лечение нейробластомы в Испании","kind":"content"},{"text":"Получите медицинскую консультацию по Комплексное лечение нейробластомы в Испании: Выбирайте среди лучших специалистов в этой области","kind":"content"},{"text":"Видеоистории пациентов Bookimed","kind":"content"},{"text":"Отзывы о Bookimed: узнайте о реальном опыте пациентов","kind":"content"},{"text":"Поделитесь этим материалом","kind":"content"},{"text":"FAQ по Комплексное лечение нейробластомы в Испании","kind":"content"},{"text":"Получить бесплатную консультацию","kind":"content"}]},"placeholders":{"price_from":"{{price_from}}","clinics_count":"{{clinics_count}}","cities_count":"{{cities_count}}","savings_pct":"{{savings_pct}}","data_date":"{{data_date}}"},"legal":{"restricted_markets":{"status":"missing","reason":"not_collected"}},"conflicts":[]}