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Joint or muscle aches and headache are possible but usually mild.","preparation":["Confirm histology and PD-L1 status","Test EGFR, ALK and other mutations","Baseline blood tests and thyroid function","Baseline chest CT or PET-CT","Screen for hepatitis B and C and tuberculosis","Review autoimmune history and current medications","Pregnancy test for women of childbearing age"],"recovery_timeline":[{"phase":"Infusion day","description":"Intravenous infusion over 30-60 minutes with observation for infusion reactions.","restrictions":["Report fever, chills or breathing difficulty immediately"]},{"phase":"Weeks 1-3 after each cycle","description":"Mild fatigue, rash or aches may occur; immune side effects can start at any time.","restrictions":["Avoid live vaccines unless approved by oncologist","Report new cough, diarrhea or jaundice promptly"]},{"phase":"Months 2-6","description":"Cycles repeat every 3-6 weeks with response imaging every 6-12 weeks.","restrictions":["Keep all scheduled blood tests and scans"]},{"phase":"Up to 2 years","description":"Treatment continues if benefit persists and side effects are manageable.","restrictions":["Late immune side effects remain possible after stopping"]}],"rehabilitation_days":null,"result_longevity":"Responses can last months to several years in responders; some patients achieve durable control after completing treatment. Duration varies widely.","revision_rate_pct":null,"scars":"None; no incisions.","sessions_or_stages":{"sessions":{"min":9,"max":35,"unit":"visits","qualifier":"Infusions every 2-6 weeks for up to 2 years, depending on agent and response."},"stages":[{"code":"baseline_assessment","label":"Baseline testing and biomarker confirmation","after":{"min":0,"max":14,"unit":"days","qualifier":"Before first infusion."}},{"code":"induction_infusions","label":"First infusions, alone or with chemotherapy","after":{"min":0,"max":84,"unit":"days","qualifier":"First 3-4 cycles from first infusion."}},{"code":"maintenance_infusions","label":"Maintenance immunotherapy infusions","after":{"min":84,"max":730,"unit":"days","qualifier":"Continues until progression, toxicity or 2 years."}}],"qualifier":"Single continuous course; number of infusions depends on agent, schedule and response."},"success":{"metric":"Overall survival at 5 years","value":32,"unit":"percent of patients alive","horizon":"5 years","population":"Advanced NSCLC with PD-L1 ≥50%, no driver mutation, on PD-1 monotherapy","evidence_status":"limited"},"techniques":[{"name":"PD-1 inhibitor monotherapy (pembrolizumab, nivolumab, cemiplimab)","suits_whom":"Advanced NSCLC with high PD-L1 expression and no driver mutation.","recovery":"No downtime; 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